CRCGN015_MCF10A_48H:A24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description (4-chloro-2-methylphenoxy)acetic acid 11.84 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN015_MCF10A_48H:A24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 3.26732
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.20684
KIF5C kinesin family member 5C 3.04861
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2.64511
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 2.24047
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.19233
KCNK5 potassium channel, two pore domain subfamily K, member 5 2.03287

decreased expression

Symbol Name Standardized Value
HSPA8 heat shock 70kDa protein 8 -3.87661
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.71513
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -3.53406
CCNB2 cyclin B2 -3.3616
CREG1 cellular repressor of E1A-stimulated genes 1 -2.63398
ZNF274 zinc finger protein 274 -2.48982
TM9SF3 transmembrane 9 superfamily member 3 -2.47903
ANXA3 annexin A3 -2.46278
LRRC8E leucine rich repeat containing 8 family, member E -2.02746