CRCGN015_MCF10A_48H:B05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

62 genes differentially expressed following the CRCGN015_MCF10A_48H:B05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABHD6 abhydrolase domain containing 6 4.51128
SRC SRC proto-oncogene, non-receptor tyrosine kinase 3.27946
BAX BCL2-associated X protein 3.0805
FPGS folylpolyglutamate synthase 2.96162
APH1A APH1A gamma secretase subunit 2.93158
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 2.81977
MICALL1 MICAL-like 1 2.50373
EXOSC4 exosome component 4 2.44249
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 2.37869
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 2.36133
TBC1D10B TBC1 domain family, member 10B 2.32209
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 2.27561
DNASE1L3 deoxyribonuclease I-like 3 2.25329
NT5DC2 5'-nucleotidase domain containing 2 2.23111
DYNLL1 dynein, light chain, LC8-type 1 2.08847
CTSZ cathepsin Z 2.07215
PLAC8 placenta-specific 8 2.02775
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.02118

decreased expression

Symbol Name Standardized Value
CDC20 cell division cycle 20 -4.36747
ACOT9 acyl-CoA thioesterase 9 -4.22263
ANXA3 annexin A3 -4.02305
TRAPPC3 trafficking protein particle complex 3 -3.44414
KIAA0319L KIAA0319-like -3.21218
RAB4A RAB4A, member RAS oncogene family -2.90177
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.86946
PLK2 polo-like kinase 2 -2.7608
HCCS holocytochrome c synthase -2.65313
AGO1 argonaute RISC catalytic component 1 -2.63537
SRBD1 S1 RNA binding domain 1 -2.61081
KRT7 keratin 7, type II -2.55454
DNALI1 dynein, axonemal, light intermediate chain 1 -2.54777
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -2.45753
CSRP2 cysteine and glycine-rich protein 2 -2.40247
LOC128966570 alpha-amylase 1B -2.32821
MOSPD2 motile sperm domain containing 2 -2.32321
NLGN4Y neuroligin 4, Y-linked -2.31187
CTBS chitobiase, di-N-acetyl- -2.24159
TRPM8 transient receptor potential cation channel, subfamily M, member 8 -2.21823
SHROOM2 shroom family member 2 -2.21421
EIF2D eukaryotic translation initiation factor 2D -2.21059
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 -2.17866
PCDHGA9 protocadherin gamma subfamily A, 9 -2.16812
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 -2.16012
AGO4 argonaute RISC catalytic component 4 -2.14969
MSH2 mutS homolog 2 -2.1429
LDHB lactate dehydrogenase B -2.12916
MRPS15 mitochondrial ribosomal protein S15 -2.10673
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific -2.09896
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -2.09334
HSF4 heat shock transcription factor 4 -2.09169
ANKRD37 ankyrin repeat domain 37 -2.07093
TMEM123 transmembrane protein 123 -2.07027
TPK1 thiamin pyrophosphokinase 1 -2.05778
ZMYM1 zinc finger, MYM-type 1 -2.05462
RTN3 reticulon 3 -2.03484
CORO2B coronin, actin binding protein, 2B -2.03283
STK38 serine/threonine kinase 38 -2.02549
ZNF778 zinc finger protein 778 -2.02524
PPP1R9A protein phosphatase 1, regulatory subunit 9A -2.02189
SNTA1 syntrophin, alpha 1 -2.0212
LYRM9 LYR motif containing 9 -2.01742
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 -2.01187