CRCGN015_MCF10A_48H:B07 Gene Set
Genes
37 genes differentially expressed following the CRCGN015_MCF10A_48H:B07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
KLHL21
|
kelch-like family member 21
|
4.08004
|
|
IER3
|
immediate early response 3
|
3.83498
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
3.80868
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.0001
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.92703
|
|
ANO10
|
anoctamin 10
|
2.75689
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.38073
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
2.3702
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
2.36261
|
|
SPRR1A
|
small proline-rich protein 1A
|
2.19941
|
|
SPRR1B
|
small proline-rich protein 1B
|
2.11146
|
|
CAB39
|
calcium binding protein 39
|
2.07341
|
|
MAPK9
|
mitogen-activated protein kinase 9
|
2.04897
|
|
HBA1
|
hemoglobin, alpha 1
|
2.02068
|
|
IL1B
|
interleukin 1, beta
|
2.00043
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MSMO1
|
methylsterol monooxygenase 1
|
-4.02995
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.74511
|
|
FBXO21
|
F-box protein 21
|
-3.4529
|
|
PLK2
|
polo-like kinase 2
|
-3.03877
|
|
CDC20
|
cell division cycle 20
|
-2.6906
|
|
SLC1A3
|
solute carrier family 1 (glial high affinity glutamate transporter), member 3
|
-2.48379
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-2.45474
|
|
IGFBP2
|
insulin-like growth factor binding protein 2, 36kDa
|
-2.38861
|
|
KIT
|
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
|
-2.28205
|
|
S100A8
|
S100 calcium binding protein A8
|
-2.22474
|
|
THSD4
|
thrombospondin, type I, domain containing 4
|
-2.20872
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-2.19316
|
|
ART3
|
ADP-ribosyltransferase 3
|
-2.19104
|
|
EPYC
|
epiphycan
|
-2.18223
|
|
ST6GALNAC5
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
|
-2.17089
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-2.15061
|
|
TAF13
|
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
|
-2.11414
|
|
ATP1B1
|
ATPase, Na+/K+ transporting, beta 1 polypeptide
|
-2.05705
|
|
CTNNAL1
|
catenin (cadherin-associated protein), alpha-like 1
|
-2.04216
|
|
CYP7A1
|
cytochrome P450, family 7, subfamily A, polypeptide 1
|
-2.03837
|
|
ZNF10
|
zinc finger protein 10
|
-2.01977
|
|
TMEM100
|
transmembrane protein 100
|
-2.00494
|
