CRCGN015_MCF10A_48H:B08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description (2s)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid 32.3 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN015_MCF10A_48H:B08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.98656
IPO13 importin 13 2.93176
BMP4 bone morphogenetic protein 4 2.86152
WIF1 WNT inhibitory factor 1 2.62804
PLSCR1 phospholipid scramblase 1 2.25461
SCRN1 secernin 1 2.15
IER3 immediate early response 3 2.14644
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.11233

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -4.29048
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.70182
ARPP19 cAMP-regulated phosphoprotein, 19kDa -3.45503
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.37498
BIRC2 baculoviral IAP repeat containing 2 -3.07515
S100A8 S100 calcium binding protein A8 -2.78393
VIM vimentin -2.24708
ANXA3 annexin A3 -2.07841
ZNF184 zinc finger protein 184 -2.05144