CRCGN015_MCF10A_48H:B16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description beta-naphthoflavone 100.0 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN015_MCF10A_48H:B16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HMOX1 heme oxygenase 1 4.69326
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 4.1628
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 3.42548
HLA-DRA major histocompatibility complex, class II, DR alpha 2.40264
EXOSC4 exosome component 4 2.38286
GADD45A growth arrest and DNA-damage-inducible, alpha 2.37505
IER3 immediate early response 3 2.34832
PPARG peroxisome proliferator-activated receptor gamma 2.24238
LACTB2 lactamase, beta 2 2.16955
GNG11 guanine nucleotide binding protein (G protein), gamma 11 2.06295
TXNRD1 thioredoxin reductase 1 2.02643

decreased expression

Symbol Name Standardized Value
ANXA3 annexin A3 -4.38799
RGS2 regulator of G-protein signaling 2 -4.31966
LAP3 leucine aminopeptidase 3 -4.09657
TES testin LIM domain protein -2.94911
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.71147
OAT ornithine aminotransferase -2.53236
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -2.39422
IGFBP7 insulin-like growth factor binding protein 7 -2.16321
ZNF586 zinc finger protein 586 -2.13259
RPIA ribose 5-phosphate isomerase A -2.01183