CRCGN015_MCF10A_48H:B17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description beta-naphthoflavone 33.33 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

30 genes differentially expressed following the CRCGN015_MCF10A_48H:B17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ZW10 zw10 kinetochore protein 5.62897
HMOX1 heme oxygenase 1 5.00454
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 4.09682
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 3.99642
SMIM40 small integral membrane protein 40 3.42879
GRWD1 glutamate-rich WD repeat containing 1 3.06652
DLK1 delta-like 1 homolog (Drosophila) 2.88593
BMP4 bone morphogenetic protein 4 2.58656
EPB41L3 erythrocyte membrane protein band 4.1-like 3 2.55648
HSPB11 heat shock protein family B (small), member 11 2.32488
EXOSC4 exosome component 4 2.29279
IER3 immediate early response 3 2.22937
PPARG peroxisome proliferator-activated receptor gamma 2.15581
SPON2 spondin 2, extracellular matrix protein 2.09715
DHRS7 dehydrogenase/reductase (SDR family) member 7 2.06613

decreased expression

Symbol Name Standardized Value
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -7.29054
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.05159
CDPF1 cysteine-rich, DPF motif domain containing 1 -3.92499
KRT7 keratin 7, type II -3.64958
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -3.5846
HEATR1 HEAT repeat containing 1 -2.94174
HPS4 Hermansky-Pudlak syndrome 4 -2.30854
MORF4L2 mortality factor 4 like 2 -2.30326
KIF4A kinesin family member 4A -2.25633
NLRP4 NLR family, pyrin domain containing 4 -2.25596
IFRD2 interferon-related developmental regulator 2 -2.16452
NTM neurotrimin -2.15789
ZMYM2 zinc finger, MYM-type 2 -2.11818
ANXA3 annexin A3 -2.05243
IGFBP7 insulin-like growth factor binding protein 7 -2.03966