CRCGN015_MCF10A_48H:B18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description beta-naphthoflavone 11.11 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN015_MCF10A_48H:B18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HMOX1 heme oxygenase 1 4.24855
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 3.1795
IER3 immediate early response 3 2.82699
CCNA1 cyclin A1 2.43775
IGHMBP2 immunoglobulin mu binding protein 2 2.42257
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 2.23321
TXNRD1 thioredoxin reductase 1 2.13522
ELAC2 elaC ribonuclease Z 2 2.10194

decreased expression

Symbol Name Standardized Value
VIM vimentin -3.76095
ANXA3 annexin A3 -3.71263
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.43402
KRT7 keratin 7, type II -2.9697
RAB4A RAB4A, member RAS oncogene family -2.61252
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -2.35251
OAT ornithine aminotransferase -2.01983