CRCGN015_MCF10A_48H:B21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dibenz(a,h)anthracene 10.95 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

61 genes differentially expressed following the CRCGN015_MCF10A_48H:B21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 5.01063
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 3.96758
SCAND1 SCAN domain containing 1 3.65024
SCRN1 secernin 1 3.28498
IER3 immediate early response 3 3.22992
ZNF589 zinc finger protein 589 3.15102
WASF3 WAS protein family, member 3 2.7689
FOSL1 FOS-like antigen 1 2.63643
CEMIP2 cell migration inducing hyaluronidase 2 2.34469
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.32725
TALDO1 transaldolase 1 2.30746
TXNRD1 thioredoxin reductase 1 2.28516
ATP5IF1 ATP synthase inhibitory factor subunit 1 2.25557
ELAC2 elaC ribonuclease Z 2 2.21652
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.21604
RANGRF RAN guanine nucleotide release factor 2.21118
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 2.19649
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.12896
TSG101 tumor susceptibility 101 2.0487
BOLA2B bolA family member 2B 2.02364
CDPF1 cysteine-rich, DPF motif domain containing 1 2.00624

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -3.99297
SNX7 sorting nexin 7 -3.93157
SLC35F2 solute carrier family 35, member F2 -3.4113
PGAM4 phosphoglycerate mutase family member 4 -3.05122
KRT14 keratin 14, type I -3.00738
PEX26 peroxisomal biogenesis factor 26 -2.65373
KAT6A K(lysine) acetyltransferase 6A -2.51746
ANKRD10 ankyrin repeat domain 10 -2.47221
KIF11 kinesin family member 11 -2.31807
CILK1 ciliogenesis associated kinase 1 -2.26596
ZG16 zymogen granule protein 16 -2.26102
MELK maternal embryonic leucine zipper kinase -2.23904
LMNB1 lamin B1 -2.20507
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 -2.19889
KRT33A keratin 33A, type I -2.1895
AHDC1 AT hook, DNA binding motif, containing 1 -2.17957
TSPAN2 tetraspanin 2 -2.17552
MIS18BP1 MIS18 binding protein 1 -2.17218
LRRC19 leucine rich repeat containing 19 -2.14004
OBP2B odorant binding protein 2B -2.13722
GRIA4 glutamate receptor, ionotropic, AMPA 4 -2.128
NFIX nuclear factor I/X (CCAAT-binding transcription factor) -2.12184
ZBTB39 zinc finger and BTB domain containing 39 -2.10298
ATP11B ATPase, class VI, type 11B -2.09452
TWNK twinkle mtDNA helicase -2.09359
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 -2.09116
SNTG2 syntrophin, gamma 2 -2.08816
HHLA2 HERV-H LTR-associating 2 -2.07456
FOXD2 forkhead box D2 -2.06281
PPP1R2C PPP1R2C family member C -2.05678
PRDM8 PR domain containing 8 -2.04879
HOXA6 homeobox A6 -2.03056
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 -2.02516
MAP3K13 mitogen-activated protein kinase kinase kinase 13 -2.02382
KRTAP1-1 keratin associated protein 1-1 -2.02346
POU4F1 POU class 4 homeobox 1 -2.01937
AKR1D1 aldo-keto reductase family 1, member D1 -2.01544
SKI SKI proto-oncogene -2.01517
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase -2.01186
ZNF254 zinc finger protein 254 -2.01063