CRCGN015_MCF10A_48H:C03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tryptamine 11.11 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

13 genes differentially expressed following the CRCGN015_MCF10A_48H:C03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MYLK myosin light chain kinase 4.67077
INTS3 integrator complex subunit 3 3.83467
SIRT3 sirtuin 3 3.37837
RIC8A RIC8 guanine nucleotide exchange factor A 2.99306
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 2.36666
ILK integrin-linked kinase 2.28132
VAMP5 vesicle-associated membrane protein 5 2.21017
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.08234

decreased expression

Symbol Name Standardized Value
DUSP6 dual specificity phosphatase 6 -2.81065
NUP85 nucleoporin 85kDa -2.46307
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.17442
SLC38A10 solute carrier family 38, member 10 -2.04168
S100A8 S100 calcium binding protein A8 -2.02314