CRCGN015_MCF10A_48H:C05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tranilast 33.33 um perturbation at 48 h in MCF10A (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

68 genes differentially expressed following the CRCGN015_MCF10A_48H:C05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 4.50762
SCRN1 secernin 1 3.32965
DLK1 delta-like 1 homolog (Drosophila) 3.30251
MAST2 microtubule associated serine/threonine kinase 2 3.21142
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 2.65734
BTBD1 BTB (POZ) domain containing 1 2.48115
KHDC4 KH domain containing 4, pre-mRNA splicing factor 2.46958
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 2.46233
BCAP29 B-cell receptor-associated protein 29 2.37897
RGS2 regulator of G-protein signaling 2 2.37375
ZCCHC10 zinc finger, CCHC domain containing 10 2.34791
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 2.31025
ATAD2B ATPase family, AAA domain containing 2B 2.27793
MAP3K5 mitogen-activated protein kinase kinase kinase 5 2.26848
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.24679
FGGY FGGY carbohydrate kinase domain containing 2.24436
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.20849
TMEM243 transmembrane protein 243, mitochondrial 2.20667
ARID4A AT rich interactive domain 4A (RBP1-like) 2.17123
ANKRD28 ankyrin repeat domain 28 2.17088
MED23 mediator complex subunit 23 2.13214
COL16A1 collagen, type XVI, alpha 1 2.1227
ZFYVE16 zinc finger, FYVE domain containing 16 2.12013
NEMF nuclear export mediator factor 2.08548
SCYL3 SCY1-like 3 (S. cerevisiae) 2.08498
H2AJ H2A.J histone 2.0787
STXBP3 syntaxin binding protein 3 2.07801
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 2.07071
LYRM1 LYR motif containing 1 2.05807
TSGA10 testis specific, 10 2.02366

decreased expression

Symbol Name Standardized Value
MT2A metallothionein 2A -5.44025
HSPA1A heat shock 70kDa protein 1A -4.92355
ENOPH1 enolase-phosphatase 1 -4.85756
CDC20 cell division cycle 20 -4.59238
LAP3 leucine aminopeptidase 3 -4.24767
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.8325
PRPF4 pre-mRNA processing factor 4 -3.3317
COG2 component of oligomeric golgi complex 2 -3.23149
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -2.85195
RPS5 ribosomal protein S5 -2.76034
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -2.72745
PLK2 polo-like kinase 2 -2.56396
SLBP stem-loop binding protein -2.50565
KRT14 keratin 14, type I -2.49949
JAG2 jagged 2 -2.47652
SF3B4 splicing factor 3b, subunit 4, 49kDa -2.44448
ZBTB35 zinc finger and BTB domain containing 35 -2.39925
CTSD cathepsin D -2.3719
CSF1R colony stimulating factor 1 receptor -2.3635
CSNK2B casein kinase 2, beta polypeptide -2.30921
FSCN1 fascin actin-bundling protein 1 -2.30786
ADA2 adenosine deaminase 2 -2.29031
MT1X metallothionein 1X -2.26425
ATG3 autophagy related 3 -2.21564
SMYD5 SMYD family member 5 -2.20999
IRF1 interferon regulatory factor 1 -2.18765
TXNRD1 thioredoxin reductase 1 -2.18739
TTLL1 tubulin tyrosine ligase-like family member 1 -2.17978
AKIP1 A kinase (PRKA) interacting protein 1 -2.11556
MRPL37 mitochondrial ribosomal protein L37 -2.09618
SDAD1 SDA1 domain containing 1 -2.07756
CTC1 CTS telomere maintenance complex component 1 -2.07448
GLOD4 glyoxalase domain containing 4 -2.05522
PRMT5 protein arginine methyltransferase 5 -2.0317
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -2.03063
PLD2 phospholipase D2 -2.02546
NID1 nidogen 1 -2.02499
LAMP3 lysosomal-associated membrane protein 3 -2.01375