| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tranilast 33.33 um perturbation at 48 h in MCF10A (Carcinogenome) |
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68 genes differentially expressed following the CRCGN015_MCF10A_48H:C05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 4.50762 |
| SCRN1 | secernin 1 | 3.32965 |
| DLK1 | delta-like 1 homolog (Drosophila) | 3.30251 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 3.21142 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 2.65734 |
| BTBD1 | BTB (POZ) domain containing 1 | 2.48115 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 2.46958 |
| KBTBD2 | kelch repeat and BTB (POZ) domain containing 2 | 2.46233 |
| BCAP29 | B-cell receptor-associated protein 29 | 2.37897 |
| RGS2 | regulator of G-protein signaling 2 | 2.37375 |
| ZCCHC10 | zinc finger, CCHC domain containing 10 | 2.34791 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 | 2.31025 |
| ATAD2B | ATPase family, AAA domain containing 2B | 2.27793 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 2.26848 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.24679 |
| FGGY | FGGY carbohydrate kinase domain containing | 2.24436 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 | 2.20849 |
| TMEM243 | transmembrane protein 243, mitochondrial | 2.20667 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 2.17123 |
| ANKRD28 | ankyrin repeat domain 28 | 2.17088 |
| MED23 | mediator complex subunit 23 | 2.13214 |
| COL16A1 | collagen, type XVI, alpha 1 | 2.1227 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 2.12013 |
| NEMF | nuclear export mediator factor | 2.08548 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | 2.08498 |
| H2AJ | H2A.J histone | 2.0787 |
| STXBP3 | syntaxin binding protein 3 | 2.07801 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 | 2.07071 |
| LYRM1 | LYR motif containing 1 | 2.05807 |
| TSGA10 | testis specific, 10 | 2.02366 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -5.44025 |
| HSPA1A | heat shock 70kDa protein 1A | -4.92355 |
| ENOPH1 | enolase-phosphatase 1 | -4.85756 |
| CDC20 | cell division cycle 20 | -4.59238 |
| LAP3 | leucine aminopeptidase 3 | -4.24767 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.8325 |
| PRPF4 | pre-mRNA processing factor 4 | -3.3317 |
| COG2 | component of oligomeric golgi complex 2 | -3.23149 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -2.85195 |
| RPS5 | ribosomal protein S5 | -2.76034 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | -2.72745 |
| PLK2 | polo-like kinase 2 | -2.56396 |
| SLBP | stem-loop binding protein | -2.50565 |
| KRT14 | keratin 14, type I | -2.49949 |
| JAG2 | jagged 2 | -2.47652 |
| SF3B4 | splicing factor 3b, subunit 4, 49kDa | -2.44448 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -2.39925 |
| CTSD | cathepsin D | -2.3719 |
| CSF1R | colony stimulating factor 1 receptor | -2.3635 |
| CSNK2B | casein kinase 2, beta polypeptide | -2.30921 |
| FSCN1 | fascin actin-bundling protein 1 | -2.30786 |
| ADA2 | adenosine deaminase 2 | -2.29031 |
| MT1X | metallothionein 1X | -2.26425 |
| ATG3 | autophagy related 3 | -2.21564 |
| SMYD5 | SMYD family member 5 | -2.20999 |
| IRF1 | interferon regulatory factor 1 | -2.18765 |
| TXNRD1 | thioredoxin reductase 1 | -2.18739 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 | -2.17978 |
| AKIP1 | A kinase (PRKA) interacting protein 1 | -2.11556 |
| MRPL37 | mitochondrial ribosomal protein L37 | -2.09618 |
| SDAD1 | SDA1 domain containing 1 | -2.07756 |
| CTC1 | CTS telomere maintenance complex component 1 | -2.07448 |
| GLOD4 | glyoxalase domain containing 4 | -2.05522 |
| PRMT5 | protein arginine methyltransferase 5 | -2.0317 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -2.03063 |
| PLD2 | phospholipase D2 | -2.02546 |
| NID1 | nidogen 1 | -2.02499 |
| LAMP3 | lysosomal-associated membrane protein 3 | -2.01375 |