CRCGN015_MCF10A_48H:C08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 15-delta-prostaglandin-j2 0.67 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN015_MCF10A_48H:C08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
WIF1 WNT inhibitory factor 1 2.7887
ARB2A ARB2 cotranscriptional regulator A 2.49984
BMP4 bone morphogenetic protein 4 2.40955
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.30893
MAP2K5 mitogen-activated protein kinase kinase 5 2.30449
TXNRD1 thioredoxin reductase 1 2.06837
NEFH neurofilament, heavy polypeptide 2.05416

decreased expression

Symbol Name Standardized Value
MT2A metallothionein 2A -3.95237
SCYL3 SCY1-like 3 (S. cerevisiae) -2.89965
CDC25B cell division cycle 25B -2.8881
FASTKD5 FAST kinase domains 5 -2.87464
STXBP2 syntaxin binding protein 2 -2.86723
STXBP1 syntaxin binding protein 1 -2.6611
HEBP1 heme binding protein 1 -2.5385
VAT1 vesicle amine transport 1 -2.26169