CRCGN015_MCF10A_48H:C12 Gene Set

Dataset	Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category	transcriptomics
Type	small molecule perturbation
Description	cimetidine 11.11 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

11 genes differentially expressed following the CRCGN015_MCF10A_48H:C12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol	Name	Standardized Value
RFX5	regulatory factor X, 5 (influences HLA class II expression)	2.50952
FPGS	folylpolyglutamate synthase	2.38802
ADAM10	ADAM metallopeptidase domain 10	2.10545
HOXA10	homeobox A10	2.05341

decreased expression

Symbol	Name	Standardized Value
VIM	vimentin	-4.67734
TUBB6	tubulin, beta 6 class V	-3.30112
GTPBP8	GTP-binding protein 8 (putative)	-2.57249
BAG3	BCL2-associated athanogene 3	-2.53503
TM9SF3	transmembrane 9 superfamily member 3	-2.51901
MT2A	metallothionein 2A	-2.35243
FKBP4	FK506 binding protein 4, 59kDa	-2.01889