CRCGN015_MCF10A_48H:C13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description oxyquinoline 101.47 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN015_MCF10A_48H:C13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 4.6665
SMIM40 small integral membrane protein 40 4.1923
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.92959
TLCD3A TLC domain containing 3A 2.73445
EPN2 epsin 2 2.54212
FPGS folylpolyglutamate synthase 2.52195
NUTF2 nuclear transport factor 2 2.5184
SNRPC small nuclear ribonucleoprotein polypeptide C 2.3725
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.30593
CEPT1 choline/ethanolamine phosphotransferase 1 2.2907
GRB14 growth factor receptor-bound protein 14 2.24995
PRR3 proline rich 3 2.2095
PROS1 protein S (alpha) 2.1691
ELAC2 elaC ribonuclease Z 2 2.15215
TIMP2 TIMP metallopeptidase inhibitor 2 2.056
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 2.04865
ECI2 enoyl-CoA delta isomerase 2 2.037

decreased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 -4.715
PLK2 polo-like kinase 2 -3.0028
S100A8 S100 calcium binding protein A8 -2.42785
ISOC1 isochorismatase domain containing 1 -2.3128
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -2.31227
TSPAN12 tetraspanin 12 -2.23185