CRCGN015_MCF10A_48H:C14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description oxyquinoline 33.82 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN015_MCF10A_48H:C14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STK25 serine/threonine kinase 25 3.74796
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 3.48531
PRKCQ protein kinase C, theta 3.05329
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.76253
SCAND1 SCAN domain containing 1 2.47983
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.15647
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 2.12466
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.08638
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 2.03262

decreased expression

Symbol Name Standardized Value
PCCB propionyl CoA carboxylase, beta polypeptide -3.76744
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.70826
KRT14 keratin 14, type I -3.42711
KAT6A K(lysine) acetyltransferase 6A -2.40418
TM9SF3 transmembrane 9 superfamily member 3 -2.37115