CRCGN015_MCF10A_48H:C15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description oxyquinoline 11.27 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN015_MCF10A_48H:C15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 4.77999
WASF3 WAS protein family, member 3 4.14895
CETN3 centrin, EF-hand protein, 3 3.77671
CORO1A coronin, actin binding protein, 1A 2.89392
NOSIP nitric oxide synthase interacting protein 2.29575
TMEM176A transmembrane protein 176A 2.27547
CD53 CD53 molecule 2.18384
WIF1 WNT inhibitory factor 1 2.14482
MYLK myosin light chain kinase 2.11858
HBA1 hemoglobin, alpha 1 2.009

decreased expression

Symbol Name Standardized Value
ANXA3 annexin A3 -4.59911
PPIC peptidylprolyl isomerase C (cyclophilin C) -4.52831
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -3.0605
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -2.51995
KCNK1 potassium channel, two pore domain subfamily K, member 1 -2.09783