CRCGN015_MCF10A_48H:C16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1-nitronaphthalene 100.97 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

12 genes differentially expressed following the CRCGN015_MCF10A_48H:C16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.91977
WIF1 WNT inhibitory factor 1 3.77919
BRCA1 breast cancer 1, early onset 3.16103
ADAT1 adenosine deaminase, tRNA-specific 1 3.00024
SPAG4 sperm associated antigen 4 2.22887
KDM5A lysine (K)-specific demethylase 5A 2.05392

decreased expression

Symbol Name Standardized Value
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -5.59203
ANXA3 annexin A3 -4.68596
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.32996
CDC20 cell division cycle 20 -3.61018
ATP11B ATPase, class VI, type 11B -2.34833
AKAP8 A kinase (PRKA) anchor protein 8 -2.0621