CRCGN015_MCF10A_48H:C17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1-nitronaphthalene 33.66 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN015_MCF10A_48H:C17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 4.37578
HBA1 hemoglobin, alpha 1 2.87029
ABHD4 abhydrolase domain containing 4 2.6353
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.22184
PECR peroxisomal trans-2-enoyl-CoA reductase 2.02764

decreased expression

Symbol Name Standardized Value
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -5.69462
BAG3 BCL2-associated athanogene 3 -4.4279
HSPA1A heat shock 70kDa protein 1A -4.36822
ZDHHC6 zinc finger, DHHC-type containing 6 -3.9892
VDAC1 voltage-dependent anion channel 1 -3.89928
ANXA3 annexin A3 -3.25406
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -3.16109
MORF4L2 mortality factor 4 like 2 -2.83392
ATG4A autophagy related 4A, cysteine peptidase -2.52569
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -2.31217