CRCGN015_MCF10A_48H:C21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description mitoxantrone 1.11 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

1067 genes differentially expressed following the CRCGN015_MCF10A_48H:C21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 8.44428
FHL2 four and a half LIM domains 2 5.55245
H2BC21 H2B clustered histone 21 4.83406
DDB2 damage-specific DNA binding protein 2, 48kDa 4.76444
SESN1 sestrin 1 4.72006
MAMLD1 mastermind-like domain containing 1 4.51717
TMEM94 transmembrane protein 94 4.44354
FDXR ferredoxin reductase 4.43168
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 4.30797
RBM15B RNA binding motif protein 15B 3.9287
KIF5C kinesin family member 5C 3.91431
H2BC12 H2B clustered histone 12 3.85212
PHF21A PHD finger protein 21A 3.78852
GPKOW G patch domain and KOW motifs 3.78628
PNKP polynucleotide kinase 3'-phosphatase 3.78484
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 3.77734
GDI1 GDP dissociation inhibitor 1 3.74678
DLK1 delta-like 1 homolog (Drosophila) 3.73604
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 3.65433
TERF2IP telomeric repeat binding factor 2, interacting protein 3.59812
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 3.5384
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 3.52582
INTS3 integrator complex subunit 3 3.50268
RTL8C retrotransposon Gag like 8C 3.44513
RGL2 ral guanine nucleotide dissociation stimulator-like 2 3.42796
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 3.41572
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 3.40942
CD83 CD83 molecule 3.39528
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.35094
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) 3.34965
WIF1 WNT inhibitory factor 1 3.32077
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2 3.25985
WDR13 WD repeat domain 13 3.21587
LSP1 lymphocyte-specific protein 1 3.20621
GORASP1 golgi reassembly stacking protein 1, 65kDa 3.19604
GNG5 guanine nucleotide binding protein (G protein), gamma 5 3.18874
EFHC1 EF-hand domain (C-terminal) containing 1 3.18022
TCEAL4 transcription elongation factor A (SII)-like 4 3.1773
CRELD1 cysteine-rich with EGF-like domains 1 3.16883
DENND4B DENN/MADD domain containing 4B 3.16693
KIF13B kinesin family member 13B 3.15524
LRRC32 leucine rich repeat containing 32 3.13864
TSPYL2 TSPY-like 2 3.10601
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.10432
NAXD NAD(P)HX dehydratase 3.09002
SARAF store-operated calcium entry-associated regulatory factor 3.07621
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 3.07563
TSPAN12 tetraspanin 12 3.03092
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 3.00164
H2AC19 H2A clustered histone 19 2.99636
GABARAPL2 GABA(A) receptor-associated protein-like 2 2.99429
ANKH ANKH inorganic pyrophosphate transport regulator 2.96834
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 2.95755
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 2.94112
WDR19 WD repeat domain 19 2.93252
AP1G2 adaptor-related protein complex 1, gamma 2 subunit 2.89413
RTL8A retrotransposon Gag like 8A 2.89281
PLXNB2 plexin B2 2.88857
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 2.88409
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.88361
TOGARAM1 TOG array regulator of axonemal microtubules 1 2.88235
IL2RA interleukin 2 receptor, alpha 2.88007
FTSJ3 FtsJ homolog 3 (E. coli) 2.87617
IL10RA interleukin 10 receptor, alpha 2.87476
ARHGAP25 Rho GTPase activating protein 25 2.86597
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1) 2.86283
TXNL4B thioredoxin-like 4B 2.85397
DYNLT1 dynein, light chain, Tctex-type 1 2.85303
MTCH1 mitochondrial carrier 1 2.84565
CUL7 cullin 7 2.83933
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 2.838
H2AC6 H2A clustered histone 6 2.83056
PRAME preferentially expressed antigen in melanoma 2.82976
FIG4 FIG4 phosphoinositide 5-phosphatase 2.81787
ZNF821 zinc finger protein 821 2.81242
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 2.81216
GSTA3 glutathione S-transferase alpha 3 2.81189
COL15A1 collagen, type XV, alpha 1 2.80364
ATG4B autophagy related 4B, cysteine peptidase 2.80135
ATF3 activating transcription factor 3 2.79444
SNED1 sushi, nidogen and EGF-like domains 1 2.79363
H1-2 H1.2 linker histone, cluster member 2.78852
SHFL shiftless antiviral inhibitor of ribosomal frameshifting 2.78789
CSRNP2 cysteine-serine-rich nuclear protein 2 2.7876
IP6K2 inositol hexakisphosphate kinase 2 2.78332
MMP2 matrix metallopeptidase 2 2.77635
CD86 CD86 molecule 2.77223
TBX19 T-box 19 2.76119
GALT galactose-1-phosphate uridylyltransferase 2.76045
TRIB1 tribbles pseudokinase 1 2.74269
PDIA5 protein disulfide isomerase family A, member 5 2.74166
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.73668
GABARAP GABA(A) receptor-associated protein 2.73165
WDR25 WD repeat domain 25 2.73005
KLHDC2 kelch domain containing 2 2.72526
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.72476
CDKL3 cyclin-dependent kinase-like 3 2.71581
RTF2 replication termination factor 2 2.71442
IL24 interleukin 24 2.71021
PPP2R2D protein phosphatase 2, regulatory subunit B, delta 2.70952
NGRN neugrin, neurite outgrowth associated 2.70652
CD80 CD80 molecule 2.70368
LOC124900388 uncharacterized LOC124900388 2.69809
SSH3 slingshot protein phosphatase 3 2.68207
SERTAD3 SERTA domain containing 3 2.67871
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 2.67719
COL3A1 collagen, type III, alpha 1 2.66826
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.66424
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 2.65865
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 2.65318
NFS1 NFS1 cysteine desulfurase 2.65283
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.65029
MTM1 myotubularin 1 2.64954
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 2.64592
GRN granulin 2.6451
ZBTB22 zinc finger and BTB domain containing 22 2.64069
TMEM59 transmembrane protein 59 2.63067
CYTH2 cytohesin 2 2.63025
IER5 immediate early response 5 2.62835
PPT1 palmitoyl-protein thioesterase 1 2.62572
PRR16 proline rich 16 2.62509
AEN apoptosis enhancing nuclease 2.62284
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 2.62191
PSME3IP1 proteasome activator subunit 3 interacting protein 1 2.61819
CTSK cathepsin K 2.61562
ACVR2A activin A receptor, type IIA 2.6148
KATNIP katanin interacting protein 2.61317
TRAFD1 TRAF-type zinc finger domain containing 1 2.6071
HSPB3 heat shock 27kDa protein 3 2.59702
IST1 increased sodium tolerance 1 homolog (yeast) 2.59376
CREM cAMP responsive element modulator 2.59262
AMPD2 adenosine monophosphate deaminase 2 2.59157
NR4A2 nuclear receptor subfamily 4, group A, member 2 2.59119
NAGK N-acetylglucosamine kinase 2.5776
ANO2 anoctamin 2, calcium activated chloride channel 2.57707
LYPLA2 lysophospholipase II 2.57646
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 2.57182
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 2.56628
ECH1 enoyl CoA hydratase 1, peroxisomal 2.55952
IL4R interleukin 4 receptor 2.55796
IRF7 interferon regulatory factor 7 2.55785
BICRA BRD4 interacting chromatin remodeling complex associated protein 2.55327
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 2.55267
GBP2 guanylate binding protein 2, interferon-inducible 2.55089
EGR3 early growth response 3 2.55051
NHLH1 nescient helix loop helix 1 2.54289
CDH12 cadherin 12, type 2 (N-cadherin 2) 2.54198
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 2.53525
RANBP10 RAN binding protein 10 2.53489
CRLF2 cytokine receptor-like factor 2 2.53035
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 2.53008
JCAD junctional cadherin 5 associated 2.52998
LUM lumican 2.52695
MLYCD malonyl-CoA decarboxylase 2.52325
ZNF331 zinc finger protein 331 2.5215
DALRD3 DALR anticodon binding domain containing 3 2.5198
SPON1 spondin 1, extracellular matrix protein 2.51926
PPP1R9A protein phosphatase 1, regulatory subunit 9A 2.51764
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 2.51441
LIN37 lin-37 DREAM MuvB core complex component 2.50928
MYLIP myosin regulatory light chain interacting protein 2.50787
OSBPL2 oxysterol binding protein-like 2 2.50614
ACADVL acyl-CoA dehydrogenase, very long chain 2.49556
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 2.49461
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 2.49269
PLAG1 pleiomorphic adenoma gene 1 2.48996
SQSTM1 sequestosome 1 2.48991
GAK cyclin G associated kinase 2.48903
NCSTN nicastrin 2.48902
TSGA10 testis specific, 10 2.48692
PLEK pleckstrin 2.48614
DUSP6 dual specificity phosphatase 6 2.48451
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.48012
INPPL1 inositol polyphosphate phosphatase-like 1 2.47801
ZNF79 zinc finger protein 79 2.47679
ZCWPW1 zinc finger, CW type with PWWP domain 1 2.47067
ACOT8 acyl-CoA thioesterase 8 2.46518
NIT1 nitrilase 1 2.46236
TMOD1 tropomodulin 1 2.46226
OR10H1 olfactory receptor, family 10, subfamily H, member 1 2.45553
SUSD4 sushi domain containing 4 2.45493
HUNK hormonally up-regulated Neu-associated kinase 2.45338
MYH4 myosin, heavy chain 4, skeletal muscle 2.45235
JAM3 junctional adhesion molecule 3 2.45161
MAGEA9B melanoma antigen family A9B 2.44878
PRX periaxin 2.44752
PEX16 peroxisomal biogenesis factor 16 2.44644
IRF9 interferon regulatory factor 9 2.44242
MBD1 methyl-CpG binding domain protein 1 2.44213
GCC1 GRIP and coiled-coil domain containing 1 2.44022
WRNIP1 Werner helicase interacting protein 1 2.43826
FHIP2B FHF complex subunit HOOK interacting protein 2B 2.43687
COLEC10 collectin sub-family member 10 (C-type lectin) 2.43587
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 2.431
CHMP2A charged multivesicular body protein 2A 2.42266
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 2.4217
NPTX2 neuronal pentraxin II 2.41838
MADD MAP-kinase activating death domain 2.4177
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 2.41533
CCDC92 coiled-coil domain containing 92 2.41093
METTL25B methyltransferase like 25B 2.41013
TCIM transcriptional and immune response regulator 2.40907
CRHBP corticotropin releasing hormone binding protein 2.40728
OR10H3 olfactory receptor, family 10, subfamily H, member 3 2.4054
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 2.40102
GPR153 G protein-coupled receptor 153 2.40077
SRPK3 SRSF protein kinase 3 2.39648
ZC3H12A zinc finger CCCH-type containing 12A 2.39456
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 2.39111
CCN6 cellular communication network factor 6 2.38918
ZNF514 zinc finger protein 514 2.38897
CANT1 calcium activated nucleotidase 1 2.38794
TMCC2 transmembrane and coiled-coil domain family 2 2.38641
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 2.37901
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 2.37736
KIF3B kinesin family member 3B 2.37561
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.37518
MYRIP myosin VIIA and Rab interacting protein 2.37509
CAMTA2 calmodulin binding transcription activator 2 2.37069
AGO1 argonaute RISC catalytic component 1 2.37038
ZFHX3 zinc finger homeobox 3 2.36986
ARRB2 arrestin, beta 2 2.36771
WASHC5 WASH complex subunit 5 2.36396
UNC5B unc-5 homolog B (C. elegans) 2.3638
TRADD TNFRSF1A-associated via death domain 2.36136
DRP2 dystrophin related protein 2 2.36115
PRSS23 protease, serine, 23 2.35777
STXBP2 syntaxin binding protein 2 2.35715
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 2.35709
NCR3 natural cytotoxicity triggering receptor 3 2.35645
AHR aryl hydrocarbon receptor 2.35639
DZANK1 double zinc ribbon and ankyrin repeat domains 1 2.35336
MAP3K7CL MAP3K7 C-terminal like 2.35291
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 2.35033
ELMO2 engulfment and cell motility 2 2.35023
ATP5F1E ATP synthase F1 subunit epsilon 2.34763
FILIP1L filamin A interacting protein 1-like 2.34719
CHD9NB CHD9 neighbor 2.34644
DKK3 dickkopf WNT signaling pathway inhibitor 3 2.34564
GPR15 G protein-coupled receptor 15 2.34508
IL6 interleukin 6 2.34348
TMEM134 transmembrane protein 134 2.34038
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 2.34002
ZNF350 zinc finger protein 350 2.33841
GJB1 gap junction protein, beta 1, 32kDa 2.33765
EOLA1 endothelium and lymphocyte associated ASCH domain 1 2.33612
BLCAP bladder cancer associated protein 2.33413
POLL polymerase (DNA directed), lambda 2.33354
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 2.33182
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 2.3312
PELI1 pellino E3 ubiquitin protein ligase 1 2.32263
FABP6 fatty acid binding protein 6, ileal 2.32207
TFEC transcription factor EC 2.31981
CLEC2D C-type lectin domain family 2, member D 2.31974
SPI1 Spi-1 proto-oncogene 2.31747
NXPE4 neurexophilin and PC-esterase domain family, member 4 2.31667
H2BC5 H2B clustered histone 5 2.31629
UPK1A uroplakin 1A 2.3151
PLK3 polo-like kinase 3 2.31431
TCEAL2 transcription elongation factor A (SII)-like 2 2.31249
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 2.31237
SAYSD1 SAYSVFN motif domain containing 1 2.30994
IL10 interleukin 10 2.30946
STON1 stonin 1 2.30852
ACTR5 ARP5 actin-related protein 5 homolog (yeast) 2.30715
DDO D-aspartate oxidase 2.30684
LIF leukemia inhibitory factor 2.30664
DAGLA diacylglycerol lipase, alpha 2.30536
DIABLO diablo, IAP-binding mitochondrial protein 2.3007
SARM1 sterile alpha and TIR motif containing 1 2.29972
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 2.29895
PAOX polyamine oxidase (exo-N4-amino) 2.29811
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 2.29716
SCN4A sodium channel, voltage gated, type IV alpha subunit 2.29676
CLTCL1 clathrin, heavy chain-like 1 2.29558
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 2.29489
ACP5 acid phosphatase 5, tartrate resistant 2.29221
MAGEC1 melanoma antigen family C1 2.28432
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.28375
GTF2B general transcription factor IIB 2.28276
LZTR1 leucine-zipper-like transcription regulator 1 2.27918
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 2.2789
H2AC7 H2A clustered histone 7 2.27831
CYB5R2 cytochrome b5 reductase 2 2.27746
S100A1 S100 calcium binding protein A1 2.27594
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.27552
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 2.27505
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.27412
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 2.27243
EFCC1 EF-hand and coiled-coil domain containing 1 2.27227
ZNF446 zinc finger protein 446 2.27103
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 2.27005
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 2.26985
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.26823
ZNF536 zinc finger protein 536 2.2647
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 2.26401
BTN2A2 butyrophilin, subfamily 2, member A2 2.26325
CD9 CD9 molecule 2.26279
PPME1 protein phosphatase methylesterase 1 2.25934
MAP3K14 mitogen-activated protein kinase kinase kinase 14 2.25927
MOSPD1 motile sperm domain containing 1 2.25901
DNAI1 dynein, axonemal, intermediate chain 1 2.25581
CCL4 chemokine (C-C motif) ligand 4 2.25571
JUP junction plakoglobin 2.25536
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 2.25504
C1QL1 complement component 1, q subcomponent-like 1 2.25458
RAB4B RAB4B, member RAS oncogene family 2.25344
SYNPO synaptopodin 2.2527
DLX5 distal-less homeobox 5 2.25202
ADAM23 ADAM metallopeptidase domain 23 2.24877
FAM114A1 family with sequence similarity 114, member A1 2.24871
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 2.247
TRIM45 tripartite motif containing 45 2.24594
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 2.2443
SETBP1 SET binding protein 1 2.24049
NR4A3 nuclear receptor subfamily 4, group A, member 3 2.23941
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 2.23843
WBP2 WW domain binding protein 2 2.23593
NCKAP1L NCK-associated protein 1-like 2.23584
DUSP2 dual specificity phosphatase 2 2.23576
RAI2 retinoic acid induced 2 2.23258
ZIM2 zinc finger, imprinted 2 2.23175
SULF1 sulfatase 1 2.23116
RGPD1 RANBP2-like and GRIP domain containing 1 2.2308
FAM90A1 family with sequence similarity 90, member A1 2.22758
PLA2G15 phospholipase A2, group XV 2.22709
OSBPL10 oxysterol binding protein-like 10 2.22662
ADGRL3 adhesion G protein-coupled receptor L3 2.22601
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 2.22564
MON1B MON1 secretory trafficking family member B 2.22506
KIAA0319L KIAA0319-like 2.22437
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 2.22373
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 2.22247
GCM1 glial cells missing homolog 1 (Drosophila) 2.22226
GNL1 guanine nucleotide binding protein-like 1 2.22163
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 2.22117
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2 2.22034
ANKRD28 ankyrin repeat domain 28 2.22023
ZMIZ1 zinc finger, MIZ-type containing 1 2.22015
G6PC2 glucose-6-phosphatase, catalytic, 2 2.21952
ELMO1 engulfment and cell motility 1 2.2194
PKDREJ polycystin (PKD) family receptor for egg jelly 2.21893
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 2.21709
PXDC1 PX domain containing 1 2.21659
TM2D1 TM2 domain containing 1 2.21632
CALCOCO1 calcium binding and coiled-coil domain 1 2.21565
PPOX protoporphyrinogen oxidase 2.21457
DNAH7 dynein, axonemal, heavy chain 7 2.21353
KDM6B lysine (K)-specific demethylase 6B 2.21339
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 2.21319
RING1 ring finger protein 1 2.21284
EIF3G eukaryotic translation initiation factor 3, subunit G 2.21258
IFNG interferon, gamma 2.21231
WSB1 WD repeat and SOCS box containing 1 2.21167
SDC4 syndecan 4 2.21074
GRM6 glutamate receptor, metabotropic 6 2.20978
THBS3 thrombospondin 3 2.20923
CISH cytokine inducible SH2-containing protein 2.20806
RHEX regulator of hemoglobinization and erythroid cell expansion 2.20773
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 2.20738
GPN2 GPN-loop GTPase 2 2.20683
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 2.20513
ZNF133 zinc finger protein 133 2.20371
MKS1 Meckel syndrome, type 1 2.20302
QSOX1 quiescin Q6 sulfhydryl oxidase 1 2.20264
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 2.2022
QTMAN queuosine-tRNA mannosyltransferase 2.2007
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 2.19944
RTP4 receptor (chemosensory) transporter protein 4 2.19899
F8 coagulation factor VIII, procoagulant component 2.19753
GNG4 guanine nucleotide binding protein (G protein), gamma 4 2.19593
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 2.19526
MCOLN1 mucolipin 1 2.19524
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.19181
GPATCH3 G patch domain containing 3 2.19089
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 2.18999
FURIN furin (paired basic amino acid cleaving enzyme) 2.18732
TH tyrosine hydroxylase 2.1871
CYBC1 cytochrome b-245 chaperone 1 2.18705
NXPH4 neurexophilin 4 2.18621
CHRM3 cholinergic receptor, muscarinic 3 2.18532
CYB5R3 cytochrome b5 reductase 3 2.1839
ZNF337 zinc finger protein 337 2.18046
CYFIP1 cytoplasmic FMR1 interacting protein 1 2.17917
AGRP agouti related neuropeptide 2.17669
UPK3A uroplakin 3A 2.1763
MUC2 mucin 2, oligomeric mucus/gel-forming 2.17389
FGF14 fibroblast growth factor 14 2.17378
RAP1GAP2 RAP1 GTPase activating protein 2 2.17319
DUSP28 dual specificity phosphatase 28 2.16704
ADAM21 ADAM metallopeptidase domain 21 2.16503
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 2.16475
NAP1L3 nucleosome assembly protein 1-like 3 2.16232
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 2.16232
RPN2 ribophorin II 2.16201
FBLN2 fibulin 2 2.1615
MAGEL2 melanoma antigen family L2 2.15947
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 2.15908
IL3RA interleukin 3 receptor, alpha (low affinity) 2.15777
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 2.15729
CIAO2B cytosolic iron-sulfur assembly component 2B 2.15641
FADD Fas (TNFRSF6)-associated via death domain 2.15589
CMKLR1 chemerin chemokine-like receptor 1 2.15542
TMEM258 transmembrane protein 258 2.15465
DNASE2B deoxyribonuclease II beta 2.15413
ACP2 acid phosphatase 2, lysosomal 2.15245
TBCC tubulin folding cofactor C 2.15214
INTS11 integrator complex subunit 11 2.15189
SHROOM2 shroom family member 2 2.15138
FYN FYN proto-oncogene, Src family tyrosine kinase 2.15089
YPEL5 yippee-like 5 (Drosophila) 2.15064
ASIC2 acid sensing (proton gated) ion channel 2 2.14708
CNGA1 cyclic nucleotide gated channel alpha 1 2.14639
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 2.14596
CADM1 cell adhesion molecule 1 2.14489
PPP1R16B protein phosphatase 1, regulatory subunit 16B 2.14408
CCDC25 coiled-coil domain containing 25 2.14209
TTI1 TELO2 interacting protein 1 2.14152
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 2.14066
B3GAT1 beta-1,3-glucuronyltransferase 1 2.14041
TBX21 T-box 21 2.14013
RNF31 ring finger protein 31 2.13941
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) 2.13545
DUSP4 dual specificity phosphatase 4 2.13538
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 2.13499
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 2.13396
FHOD1 formin homology 2 domain containing 1 2.13382
HDLBP high density lipoprotein binding protein 2.13337
LUC7L LUC7-like (S. cerevisiae) 2.13053
CCL3L3 chemokine (C-C motif) ligand 3-like 3 2.13028
FRY furry homolog (Drosophila) 2.12905
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 2.12885
AICDA activation-induced cytidine deaminase 2.12822
ATOSB atos homolog B 2.12792
FSTL4 follistatin-like 4 2.12697
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 2.12622
TXNRD2 thioredoxin reductase 2 2.12621
IL12B interleukin 12B 2.12369
KLHL21 kelch-like family member 21 2.12351
MC2R melanocortin 2 receptor (adrenocorticotropic hormone) 2.1232
XPC xeroderma pigmentosum, complementation group C 2.12273
WFS1 Wolfram syndrome 1 (wolframin) 2.12196
BCL9 B-cell CLL/lymphoma 9 2.12102
PTPRF protein tyrosine phosphatase, receptor type, F 2.11995
PECR peroxisomal trans-2-enoyl-CoA reductase 2.11986
GRAMD1C GRAM domain containing 1C 2.11972
DNM3 dynamin 3 2.11898
MYO15A myosin XVA 2.11867
TRIM62 tripartite motif containing 62 2.11766
TRAF4 TNF receptor-associated factor 4 2.11692
WDR5B WD repeat domain 5B 2.11582
STAMBP STAM binding protein 2.11408
CACFD1 calcium channel flower domain containing 1 2.11335
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 2.11209
IL5 interleukin 5 2.11201
DACH1 dachshund family transcription factor 1 2.11022
COL9A2 collagen, type IX, alpha 2 2.10982
SPHK2 sphingosine kinase 2 2.10912
DCTN1 dynactin 1 2.10901
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B 2.10787
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit 2.10784
IQSEC2 IQ motif and Sec7 domain 2 2.10767
ZG16 zymogen granule protein 16 2.1075
NENF neudesin neurotrophic factor 2.10728
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 2.10631
RWDD2A RWD domain containing 2A 2.10408
IGHMBP2 immunoglobulin mu binding protein 2 2.10357
NPPA natriuretic peptide A 2.10332
REEP2 receptor accessory protein 2 2.09866
SYN2 synapsin II 2.09782
HLA-C major histocompatibility complex, class I, C 2.09686
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 2.09669
APOBR apolipoprotein B receptor 2.09527
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 2.09481
SETD1A SET domain containing 1A 2.09464
PCBP3 poly(rC) binding protein 3 2.09453
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2.09346
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 2.09304
NECAP2 NECAP endocytosis associated 2 2.08991
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1 2.0899
APOL1 apolipoprotein L, 1 2.0896
DNAH17 dynein, axonemal, heavy chain 17 2.08932
ZCCHC2 zinc finger, CCHC domain containing 2 2.08872
TYROBP TYRO protein tyrosine kinase binding protein 2.08763
YEATS2 YEATS domain containing 2 2.08645
ACTN3 actinin, alpha 3 (gene/pseudogene) 2.08624
DENND4A DENN/MADD domain containing 4A 2.08618
CDX2 caudal type homeobox 2 2.0859
DCTN6 dynactin 6 2.08492
ENAH enabled homolog (Drosophila) 2.08491
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 2.08483
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) 2.08415
MED9 mediator complex subunit 9 2.08274
SERHL2 serine hydrolase-like 2 2.08241
AMIGO2 adhesion molecule with Ig-like domain 2 2.0817
GABARAPL1 GABA(A) receptor-associated protein like 1 2.08107
EMC9 ER membrane protein complex subunit 9 2.07861
SRP54 signal recognition particle 54kDa 2.07842
CD101 CD101 molecule 2.07832
PFN2 profilin 2 2.07823
TMC6 transmembrane channel-like 6 2.07688
SNAP91 synaptosomal-associated protein, 91kDa 2.07676
NAPSA napsin A aspartic peptidase 2.07558
CHRM2 cholinergic receptor, muscarinic 2 2.07491
BCKDK branched chain ketoacid dehydrogenase kinase 2.0745
REM1 RAS (RAD and GEM)-like GTP-binding 1 2.07425
ZFYVE26 zinc finger, FYVE domain containing 26 2.07417
EXOC6B exocyst complex component 6B 2.07304
EFNB1 ephrin-B1 2.07104
ZNF248 zinc finger protein 248 2.06824
TMPRSS5 transmembrane protease, serine 5 2.0675
BTG4 B-cell translocation gene 4 2.0675
LOC100533997 MAGEA10-MAGEA5 readthrough 2.06695
IL9R interleukin 9 receptor 2.06688
MKNK1 MAP kinase interacting serine/threonine kinase 1 2.06368
DNAI4 dynein axonemal intermediate chain 4 2.06244
MXI1 MAX interactor 1, dimerization protein 2.06243
NSFL1C NSFL1 (p97) cofactor (p47) 2.06189
RANBP17 RAN binding protein 17 2.06182
CXCR5 chemokine (C-X-C motif) receptor 5 2.06176
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 2.06009
LMAN2L lectin, mannose-binding 2-like 2.05907
PRH1-TAS2R14 PRH1-TAS2R14 readthrough 2.05824
TUBAL3 tubulin, alpha-like 3 2.0582
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 2.05754
BEX4 brain expressed, X-linked 4 2.05713
AFF2 AF4/FMR2 family, member 2 2.0558
UFC1 ubiquitin-fold modifier conjugating enzyme 1 2.05542
HTRA2 HtrA serine peptidase 2 2.05438
MAGED2 melanoma antigen family D2 2.054
OTULINL OTU deubiquitinase with linear linkage specificity like 2.0526
LDOC1 leucine zipper, down-regulated in cancer 1 2.05078
LIMD2 LIM domain containing 2 2.04797
INHBB inhibin, beta B 2.04744
FGF18 fibroblast growth factor 18 2.04591
PHOX2B paired-like homeobox 2b 2.04526
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 2.04422
ELAVL4 ELAV like neuron-specific RNA binding protein 4 2.04331
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 2.04059
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.04011
PTPRE protein tyrosine phosphatase, receptor type, E 2.03817
IFIH1 interferon induced with helicase C domain 1 2.03783
WHRN whirlin 2.03761
ATXN1 ataxin 1 2.03676
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 2.03642
PHAF1 phagosome assembly factor 1 2.03611
SEC14L5 SEC14-like 5 (S. cerevisiae) 2.03584
HLA-DRA major histocompatibility complex, class II, DR alpha 2.03457
TCEAL1 transcription elongation factor A (SII)-like 1 2.03408
EXOC7 exocyst complex component 7 2.03306
SIGLEC15 sialic acid binding Ig-like lectin 15 2.0319
BTG1 B-cell translocation gene 1, anti-proliferative 2.03152
IFT27 intraflagellar transport 27 2.03108
TRIM21 tripartite motif containing 21 2.03048
GSTM3 glutathione S-transferase mu 3 (brain) 2.03023
IRS2 insulin receptor substrate 2 2.03006
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 2.02922
KLK1 kallikrein 1 2.02602
CLUL1 clusterin-like 1 (retinal) 2.02544
ZNF75D zinc finger protein 75D 2.02532
STX5 syntaxin 5 2.02472
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 2.02389
LEFTY1 left-right determination factor 1 2.02367
KRT12 keratin 12, type I 2.02315
NTAN1 N-terminal asparagine amidase 2.02294
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 2.0229
TIMP1 TIMP metallopeptidase inhibitor 1 2.02273
IP6K1 inositol hexakisphosphate kinase 1 2.02199
PTP4A3 protein tyrosine phosphatase type IVA, member 3 2.02147
SKIC2 SKI2 subunit of superkiller complex 2.02135
IL11 interleukin 11 2.02045
PRKX protein kinase, X-linked 2.01921
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 2.01854
SYP synaptophysin 2.01688
PCDHA3 protocadherin alpha 3 2.01679
GUK1 guanylate kinase 1 2.01434
HAO1 hydroxyacid oxidase (glycolate oxidase) 1 2.01298
CCR3 chemokine (C-C motif) receptor 3 2.01266
KLHL36 kelch-like family member 36 2.01266
MMP3 matrix metallopeptidase 3 2.01232
MSI1 musashi RNA-binding protein 1 2.01229
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) 2.01199
SV2C synaptic vesicle glycoprotein 2C 2.01166
CHPF2 chondroitin polymerizing factor 2 2.0104
KAT2B K(lysine) acetyltransferase 2B 2.01016
JMJD4 jumonji domain containing 4 2.00972
OR7A17 olfactory receptor, family 7, subfamily A, member 17 2.00871
SBDS Shwachman-Bodian-Diamond syndrome 2.00844
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 2.00733
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 2.00729
MYD88 myeloid differentiation primary response 88 2.00605
DAPL1 death associated protein-like 1 2.00574
RTN1 reticulon 1 2.00524
IL20RA interleukin 20 receptor, alpha 2.00438
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 2.00434
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 2.00344
CDK5RAP1 CDK5 regulatory subunit associated protein 1 2.00339
S100G S100 calcium binding protein G 2.00336
GRIK4 glutamate receptor, ionotropic, kainate 4 2.00206
NOPCHAP1 NOP protein chaperone 1 2.0012
BECN1 beclin 1, autophagy related 2.0009

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -9.64168
KIF14 kinesin family member 14 -7.51017
CDK1 cyclin-dependent kinase 1 -7.37995
PCNA proliferating cell nuclear antigen -7.22829
CDC20 cell division cycle 20 -6.71009
CCNA2 cyclin A2 -6.67292
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -6.27813
ELOVL6 ELOVL fatty acid elongase 6 -6.2137
CCNB2 cyclin B2 -5.8823
MCM6 minichromosome maintenance complex component 6 -5.81608
MELK maternal embryonic leucine zipper kinase -5.78448
KIF11 kinesin family member 11 -5.76404
DCK deoxycytidine kinase -5.72515
TTK TTK protein kinase -5.63295
S100A8 S100 calcium binding protein A8 -5.61988
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -5.61543
TOP2A topoisomerase (DNA) II alpha 170kDa -5.59894
TM9SF3 transmembrane 9 superfamily member 3 -5.42801
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -5.36586
HACD3 3-hydroxyacyl-CoA dehydratase 3 -5.34532
PLK1 polo-like kinase 1 -5.29435
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -5.22064
MCM10 minichromosome maintenance complex component 10 -5.1916
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -5.15408
DEPDC1 DEP domain containing 1 -5.13314
KIF20A kinesin family member 20A -5.06637
EXO1 exonuclease 1 -5.00175
BIRC5 baculoviral IAP repeat containing 5 -4.96694
NEK2 NIMA-related kinase 2 -4.85243
NCAPG2 non-SMC condensin II complex, subunit G2 -4.84116
ANXA3 annexin A3 -4.82088
CHEK1 checkpoint kinase 1 -4.7925
RACGAP1 Rac GTPase activating protein 1 -4.64857
KIF23 kinesin family member 23 -4.56023
CEP55 centrosomal protein 55kDa -4.51993
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -4.48271
PRC1 protein regulator of cytokinesis 1 -4.42518
SPC25 SPC25, NDC80 kinetochore complex component -4.38795
KIF18A kinesin family member 18A -4.38483
ATAD2 ATPase family, AAA domain containing 2 -4.38345
CENPU centromere protein U -4.37334
HMMR hyaluronan-mediated motility receptor (RHAMM) -4.33898
OAT ornithine aminotransferase -4.31651
RFC3 replication factor C (activator 1) 3, 38kDa -4.29416
TRIP13 thyroid hormone receptor interactor 13 -4.24384
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -4.19453
KIF4A kinesin family member 4A -4.11027
STMN1 stathmin 1 -4.08386
GINS2 GINS complex subunit 2 (Psf2 homolog) -4.07842
RRM1 ribonucleotide reductase M1 -4.07129
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -4.02954
LMNB1 lamin B1 -4.00869
TPX2 TPX2, microtubule-associated -3.98846
SMC4 structural maintenance of chromosomes 4 -3.9874
MYC v-myc avian myelocytomatosis viral oncogene homolog -3.97612
DBF4 DBF4 zinc finger -3.95726
TMPO thymopoietin -3.95186
CPAP centrosome assembly and centriole elongation protein -3.92108
CDK2 cyclin-dependent kinase 2 -3.8957
DHFR dihydrofolate reductase -3.88552
NUSAP1 nucleolar and spindle associated protein 1 -3.86735
MKI67 marker of proliferation Ki-67 -3.85697
CDC45 cell division cycle 45 -3.83581
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.81479
FANCI Fanconi anemia, complementation group I -3.79171
SHCBP1 SHC SH2-domain binding protein 1 -3.78448
MCM5 minichromosome maintenance complex component 5 -3.73606
MRPS2 mitochondrial ribosomal protein S2 -3.7331
NCAPG non-SMC condensin I complex, subunit G -3.71623
PBK PDZ binding kinase -3.69194
PARPBP PARP1 binding protein -3.68904
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -3.67414
DONSON downstream neighbor of SON -3.6623
BIRC2 baculoviral IAP repeat containing 2 -3.65799
ALG9 ALG9, alpha-1,2-mannosyltransferase -3.65766
TIPIN TIMELESS interacting protein -3.65529
DLAT dihydrolipoamide S-acetyltransferase -3.64838
PCLAF PCNA clamp associated factor -3.63723
SPAG5 sperm associated antigen 5 -3.6291
CENPN centromere protein N -3.61026
FXN frataxin -3.60454
HJURP Holliday junction recognition protein -3.58465
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -3.56954
CDC6 cell division cycle 6 -3.53723
CKS2 CDC28 protein kinase regulatory subunit 2 -3.50464
ERCC6L excision repair cross-complementation group 6-like -3.49765
XPOT exportin, tRNA -3.49429
CKAP2 cytoskeleton associated protein 2 -3.48717
ZWINT ZW10 interacting kinetochore protein -3.48043
FOXM1 forkhead box M1 -3.47706
ECT2 epithelial cell transforming 2 -3.46822
RRM2 ribonucleotide reductase M2 -3.462
MCM4 minichromosome maintenance complex component 4 -3.40469
CENPA centromere protein A -3.40002
YAP1 Yes-associated protein 1 -3.39762
ZWILCH zwilch kinetochore protein -3.39362
OIP5 Opa interacting protein 5 -3.39087
TARS1 threonyl-tRNA synthetase 1 -3.39018
CDK4 cyclin-dependent kinase 4 -3.38031
CDKN3 cyclin-dependent kinase inhibitor 3 -3.37038
NDC1 NDC1 transmembrane nucleoporin -3.35556
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.33574
TLCD3A TLC domain containing 3A -3.31961
UNG uracil-DNA glycosylase -3.30676
NDC80 NDC80 kinetochore complex component -3.30335
EXOSC9 exosome component 9 -3.28107
LBR lamin B receptor -3.26272
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) -3.25289
GUF1 GUF1 GTPase homolog (S. cerevisiae) -3.24916
SNRPA small nuclear ribonucleoprotein polypeptide A -3.23954
TMEM38B transmembrane protein 38B -3.23814
SEPHS1 selenophosphate synthetase 1 -3.23447
GPHN gephyrin -3.21999
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -3.19969
H2AZ1 H2A.Z variant histone 1 -3.19665
SCD stearoyl-CoA desaturase (delta-9-desaturase) -3.18976
CRTAP cartilage associated protein -3.17454
IARS1 isoleucyl-tRNA synthetase 1 -3.16791
CENPM centromere protein M -3.14242
INSIG1 insulin induced gene 1 -3.13293
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -3.12884
CDCA3 cell division cycle associated 3 -3.12511
HNRNPF heterogeneous nuclear ribonucleoprotein F -3.11394
PLK4 polo-like kinase 4 -3.11305
RXYLT1 ribitol xylosyltransferase 1 -3.10899
MCM7 minichromosome maintenance complex component 7 -3.08151
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -3.07551
HMGB2 high mobility group box 2 -3.0734
NEIL3 nei endonuclease VIII-like 3 (E. coli) -3.06399
ASF1B anti-silencing function 1B histone chaperone -3.04532
PALS1 protein associated with LIN7 1, MAGUK p55 family member -3.03769
NQO2 NAD(P)H dehydrogenase, quinone 2 -3.03596
EXOC5 exocyst complex component 5 -3.02387
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -3.0238
PLK2 polo-like kinase 2 -3.01885
FBXO5 F-box protein 5 -3.01373
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -3.00215
RBBP4 retinoblastoma binding protein 4 -2.99955
KPNA3 karyopherin alpha 3 (importin alpha 4) -2.98007
BRCA1 breast cancer 1, early onset -2.97885
PARP1 poly (ADP-ribose) polymerase 1 -2.97673
RMI1 RecQ mediated genome instability 1 -2.97392
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -2.96937
PRKDC protein kinase, DNA-activated, catalytic polypeptide -2.96177
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 -2.96089
FEN1 flap structure-specific endonuclease 1 -2.95415
SUMF2 sulfatase modifying factor 2 -2.94709
VRK1 vaccinia related kinase 1 -2.94509
WDHD1 WD repeat and HMG-box DNA binding protein 1 -2.94455
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 -2.93723
C1QBP complement component 1, q subcomponent binding protein -2.93445
CDCA8 cell division cycle associated 8 -2.93013
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -2.92817
UBE2C ubiquitin-conjugating enzyme E2C -2.92265
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.92156
NUP155 nucleoporin 155kDa -2.91752
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -2.91739
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -2.91476
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.9139
KIF15 kinesin family member 15 -2.87447
POLR1F RNA polymerase I subunit F -2.86769
AURKA aurora kinase A -2.86764
CCNB1 cyclin B1 -2.86481
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -2.85737
EXOSC8 exosome component 8 -2.84817
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.84161
IDE insulin-degrading enzyme -2.83637
BICD2 bicaudal D homolog 2 (Drosophila) -2.8345
ACSL1 acyl-CoA synthetase long-chain family member 1 -2.82146
RFC4 replication factor C (activator 1) 4, 37kDa -2.82031
NUP54 nucleoporin 54kDa -2.81786
MIS18A MIS18 kinetochore protein A -2.81462
SEH1L SEH1-like (S. cerevisiae) -2.81114
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) -2.80155
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 -2.80058
GABPA GA binding protein transcription factor, alpha subunit 60kDa -2.78937
DDIT4 DNA-damage-inducible transcript 4 -2.78927
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.78581
CDC25C cell division cycle 25C -2.78477
HACD2 3-hydroxyacyl-CoA dehydratase 2 -2.78253
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.77128
CDC25B cell division cycle 25B -2.76729
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.76429
DNA2 DNA replication helicase/nuclease 2 -2.75983
IPO5 importin 5 -2.7534
HEATR1 HEAT repeat containing 1 -2.75072
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa -2.74957
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.74899
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -2.74545
LDHB lactate dehydrogenase B -2.7366
ZBTB35 zinc finger and BTB domain containing 35 -2.73523
CENPS-CORT CENPS-CORT readthrough -2.73175
SKA1 spindle and kinetochore associated complex subunit 1 -2.72958
GTSE1 G-2 and S-phase expressed 1 -2.72943
VASH2 vasohibin 2 -2.7174
NOLC1 nucleolar and coiled-body phosphoprotein 1 -2.70828
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -2.70814
PRMT3 protein arginine methyltransferase 3 -2.70133
CHPT1 choline phosphotransferase 1 -2.70076
H1-10 H1.10 linker histone -2.69569
NPR2 natriuretic peptide receptor 2 -2.6938
MPZL1 myelin protein zero-like 1 -2.68068
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.67884
NCAPH non-SMC condensin I complex, subunit H -2.67679
WDR43 WD repeat domain 43 -2.67305
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -2.67211
TMOD3 tropomodulin 3 (ubiquitous) -2.66593
MRS2 MRS2 magnesium transporter -2.66517
KIF18B kinesin family member 18B -2.65884
SRSF3 serine/arginine-rich splicing factor 3 -2.65836
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.65491
MICB MHC class I polypeptide-related sequence B -2.65434
CDK7 cyclin-dependent kinase 7 -2.63719
OXCT1 3-oxoacid CoA transferase 1 -2.63574
FKBP14 FK506 binding protein 14, 22 kDa -2.63516
SUZ12 SUZ12 polycomb repressive complex 2 subunit -2.6317
PTTG1 pituitary tumor-transforming 1 -2.62231
MRPL3 mitochondrial ribosomal protein L3 -2.62107
FAM216A family with sequence similarity 216, member A -2.61242
MANEA mannosidase, endo-alpha -2.59242
TXLNG taxilin gamma -2.57004
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.56702
PPP6C protein phosphatase 6, catalytic subunit -2.56547
IPO7 importin 7 -2.55672
BLMH bleomycin hydrolase -2.55417
CAND1 cullin-associated and neddylation-dissociated 1 -2.5523
SPPL2A signal peptide peptidase like 2A -2.54987
TECR trans-2,3-enoyl-CoA reductase -2.54555
COASY CoA synthase -2.53822
CENPI centromere protein I -2.51398
THOP1 thimet oligopeptidase 1 -2.50998
UBE2J1 ubiquitin-conjugating enzyme E2, J1 -2.5096
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -2.50675
RBBP8 retinoblastoma binding protein 8 -2.50191
DHCR7 7-dehydrocholesterol reductase -2.50011
CDK6 cyclin-dependent kinase 6 -2.49839
SH3D19 SH3 domain containing 19 -2.49574
ZDHHC6 zinc finger, DHHC-type containing 6 -2.49563
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -2.49339
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -2.49013
DBR1 debranching RNA lariats 1 -2.48824
TACC3 transforming, acidic coiled-coil containing protein 3 -2.48598
FKBP5 FK506 binding protein 5 -2.47954
CASP8AP2 caspase 8 associated protein 2 -2.47342
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -2.46964
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.46961
CAPRIN1 cell cycle associated protein 1 -2.46908
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.46755
NNT nicotinamide nucleotide transhydrogenase -2.4671
ANKRD40 ankyrin repeat domain 40 -2.46023
NOL8 nucleolar protein 8 -2.45845
RAB33B RAB33B, member RAS oncogene family -2.45282
ORC6 origin recognition complex, subunit 6 -2.44955
SLC35F2 solute carrier family 35, member F2 -2.44512
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -2.43787
CDH4 cadherin 4, type 1, R-cadherin (retinal) -2.43701
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.4256
LARP4 La ribonucleoprotein domain family, member 4 -2.42541
SLC25A46 solute carrier family 25, member 46 -2.41585
CORO1C coronin, actin binding protein, 1C -2.41338
PALM2AKAP2 PALM2 and AKAP2 fusion -2.4132
STIL SCL/TAL1 interrupting locus -2.40938
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -2.40884
TSPAN3 tetraspanin 3 -2.40821
HADH hydroxyacyl-CoA dehydrogenase -2.40703
AP1AR adaptor-related protein complex 1 associated regulatory protein -2.39833
DKK1 dickkopf WNT signaling pathway inhibitor 1 -2.39814
USP1 ubiquitin specific peptidase 1 -2.3978
SHMT1 serine hydroxymethyltransferase 1 (soluble) -2.39671
WAPL WAPL cohesin release factor -2.39661
YEATS4 YEATS domain containing 4 -2.39637
BARD1 BRCA1 associated RING domain 1 -2.39479
PMPCA peptidase (mitochondrial processing) alpha -2.39472
PTBP1 polypyrimidine tract binding protein 1 -2.39248
NUP160 nucleoporin 160kDa -2.38862
SET SET nuclear proto-oncogene -2.38735
API5 apoptosis inhibitor 5 -2.38565
UGCG UDP-glucose ceramide glucosyltransferase -2.38506
FASTKD3 FAST kinase domains 3 -2.38365
NUP205 nucleoporin 205kDa -2.38363
NMD3 NMD3 ribosome export adaptor -2.38306
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -2.38225
CRLF3 cytokine receptor-like factor 3 -2.37279
MRPL34 mitochondrial ribosomal protein L34 -2.37221
CLIC4 chloride intracellular channel 4 -2.3682
TTC27 tetratricopeptide repeat domain 27 -2.36256
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein -2.35982
RPA3 replication protein A3, 14kDa -2.34997
NCAPD3 non-SMC condensin II complex, subunit D3 -2.34236
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.3419
CDCA4 cell division cycle associated 4 -2.3383
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -2.33815
KLHL7 kelch-like family member 7 -2.33567
SPDL1 spindle apparatus coiled-coil protein 1 -2.33551
CHUK conserved helix-loop-helix ubiquitous kinase -2.33389
LOC128031832 uncharacterized LOC128031832 -2.33362
MSH2 mutS homolog 2 -2.32638
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.32468
SBNO1 strawberry notch homolog 1 (Drosophila) -2.32211
LYRM2 LYR motif containing 2 -2.31479
COQ3 coenzyme Q3 methyltransferase -2.31055
PEBP1 phosphatidylethanolamine binding protein 1 -2.30717
PDS5A PDS5 cohesin associated factor A -2.3057
THEM6 thioesterase superfamily member 6 -2.3052
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.30507
ACSL3 acyl-CoA synthetase long-chain family member 3 -2.30302
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 -2.3024
RPIA ribose 5-phosphate isomerase A -2.30234
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -2.29486
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 -2.28716
SIGMAR1 sigma non-opioid intracellular receptor 1 -2.28636
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -2.28495
BAHCC1 BAH domain and coiled-coil containing 1 -2.28259
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -2.27902
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -2.27686
PFAS phosphoribosylformylglycinamidine synthase -2.27544
GTPBP8 GTP-binding protein 8 (putative) -2.27338
TMEM123 transmembrane protein 123 -2.27081
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.26927
SCYL2 SCY1-like 2 (S. cerevisiae) -2.26915
DAND5 DAN domain family member 5, BMP antagonist -2.26722
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -2.26075
XPO1 exportin 1 -2.26006
HELLS helicase, lymphoid-specific -2.26004
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -2.25857
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.25658
TIMCC TIM double twin CX3C motif chaperone -2.25627
CEP76 centrosomal protein 76kDa -2.25579
PIMREG PICALM interacting mitotic regulator -2.25141
ARMC1 armadillo repeat containing 1 -2.24253
ENOPH1 enolase-phosphatase 1 -2.2388
WDR76 WD repeat domain 76 -2.2362
PSPH phosphoserine phosphatase -2.23612
DCBLD2 discoidin, CUB and LCCL domain containing 2 -2.23596
RFC2 replication factor C (activator 1) 2, 40kDa -2.23185
GMPS guanine monphosphate synthase -2.22949
CCNC cyclin C -2.22888
GEMIN4 gem (nuclear organelle) associated protein 4 -2.22806
BLM Bloom syndrome, RecQ helicase-like -2.2272
RNF38 ring finger protein 38 -2.22684
CPVL carboxypeptidase, vitellogenic-like -2.22474
RPP40 ribonuclease P/MRP 40kDa subunit -2.22434
CBX3 chromobox homolog 3 -2.22195
HDDC2 HD domain containing 2 -2.22106
HMGB1 high mobility group box 1 -2.21962
MICA MHC class I polypeptide-related sequence A -2.21699
PPID peptidylprolyl isomerase D -2.21473
TMEM267 transmembrane protein 267 -2.21091
KIF20B kinesin family member 20B -2.20971
MRPL35 mitochondrial ribosomal protein L35 -2.20578
ERLIN1 ER lipid raft associated 1 -2.20514
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase -2.2046
ENDOG endonuclease G -2.2034
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.20235
WAC WW domain containing adaptor with coiled-coil -2.20092
SCML2 sex comb on midleg-like 2 (Drosophila) -2.20059
ECD ecdysoneless homolog (Drosophila) -2.20052
HAUS4 HAUS augmin-like complex, subunit 4 -2.19718
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 -2.1971
CCDC59 coiled-coil domain containing 59 -2.19656
CENPF centromere protein F, 350/400kDa -2.19471
DAZAP1 DAZ associated protein 1 -2.19123
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 -2.19094
ANAPC10 anaphase promoting complex subunit 10 -2.18847
RRP1B ribosomal RNA processing 1B -2.18261
CBR3 carbonyl reductase 3 -2.18231
NME4 NME/NM23 nucleoside diphosphate kinase 4 -2.18051
ENTR1 endosome associated trafficking regulator 1 -2.17838
AGMAT agmatine ureohydrolase (agmatinase) -2.1777
TMX1 thioredoxin-related transmembrane protein 1 -2.17601
SLC25A40 solute carrier family 25, member 40 -2.17192
CHD1 chromodomain helicase DNA binding protein 1 -2.16991
POU2AF1 POU class 2 associating factor 1 -2.16805
MSH6 mutS homolog 6 -2.1658
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.1629
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -2.16152
RDX radixin -2.16036
BOP1 block of proliferation 1 -2.15358
ASB7 ankyrin repeat and SOCS box containing 7 -2.15351
SRPK1 SRSF protein kinase 1 -2.15255
RBM14-RBM4 RBM14-RBM4 readthrough -2.14625
RPH3A rabphilin 3A -2.14446
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.14351
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.14291
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -2.14046
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -2.13907
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit -2.13813
SP2 Sp2 transcription factor -2.13779
PCYOX1 prenylcysteine oxidase 1 -2.13588
ABHD17B abhydrolase domain containing 17B -2.13456
SMAGP small cell adhesion glycoprotein -2.12936
AK4 adenylate kinase 4 -2.12736
TMEM33 transmembrane protein 33 -2.12525
ARL5A ADP-ribosylation factor-like 5A -2.12471
TMEM243 transmembrane protein 243, mitochondrial -2.12283
EGFR epidermal growth factor receptor -2.11738
MRPS33 mitochondrial ribosomal protein S33 -2.11479
AHCTF1 AT hook containing transcription factor 1 -2.11423
CDC23 cell division cycle 23 -2.11304
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like -2.10692
FAM20B family with sequence similarity 20, member B -2.10645
IGLL1 immunoglobulin lambda-like polypeptide 1 -2.10227
SLC35A5 solute carrier family 35, member A5 -2.10085
TUBD1 tubulin, delta 1 -2.1007
CISD1 CDGSH iron sulfur domain 1 -2.09626
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.09612
TDP1 tyrosyl-DNA phosphodiesterase 1 -2.09578
PTGES prostaglandin E synthase -2.09492
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -2.0924
ANKRD49 ankyrin repeat domain 49 -2.09182
BCAP29 B-cell receptor-associated protein 29 -2.08675
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) -2.08451
MAPK14 mitogen-activated protein kinase 14 -2.08365
MTFR1 mitochondrial fission regulator 1 -2.083
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -2.08197
CCNE2 cyclin E2 -2.08023
COLGALT1 collagen beta(1-O)galactosyltransferase 1 -2.07941
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -2.0789
GABPB1 GA binding protein transcription factor, beta subunit 1 -2.07889
PRUNE1 prune exopolyphosphatase 1 -2.07831
HDAC2 histone deacetylase 2 -2.07806
LTF lactotransferrin -2.07516
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -2.0731
MAGT1 magnesium transporter 1 -2.07285
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -2.07269
JPT1 Jupiter microtubule associated homolog 1 -2.06847
LARP1 La ribonucleoprotein domain family, member 1 -2.0683
PROS1 protein S (alpha) -2.06724
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -2.06711
AFG3L2 AFG3-like AAA ATPase 2 -2.06546
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -2.0628
RANBP9 RAN binding protein 9 -2.0624
MRPL42 mitochondrial ribosomal protein L42 -2.06119
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -2.06046
NUP37 nucleoporin 37kDa -2.05679
TK1 thymidine kinase 1, soluble -2.05449
PRDX4 peroxiredoxin 4 -2.05249
EXPH5 exophilin 5 -2.04917
EMC8 ER membrane protein complex subunit 8 -2.04868
CTPS2 CTP synthase 2 -2.04453
CBFB core-binding factor, beta subunit -2.0417
U2SURP U2 snRNP-associated SURP domain containing -2.04143
RAB27A RAB27A, member RAS oncogene family -2.03851
NEMP1 nuclear envelope integral membrane protein 1 -2.03596
METTL16 methyltransferase like 16 -2.03488
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -2.03106
NUP88 nucleoporin 88kDa -2.02738
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -2.02567
CSE1L CSE1 chromosome segregation 1-like (yeast) -2.0214
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) -2.02089
XPO4 exportin 4 -2.02078
WDR18 WD repeat domain 18 -2.01995
UBIAD1 UbiA prenyltransferase domain containing 1 -2.01971
TWSG1 twisted gastrulation BMP signaling modulator 1 -2.01844
PRMT5 protein arginine methyltransferase 5 -2.01655
CDC73 cell division cycle 73 -2.01628
TOP2B topoisomerase (DNA) II beta 180kDa -2.015
KDM1A lysine (K)-specific demethylase 1A -2.01313
SRSF1 serine/arginine-rich splicing factor 1 -2.0115
RAD51AP1 RAD51 associated protein 1 -2.00928
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -2.00821
CCT4 chaperonin containing TCP1, subunit 4 (delta) -2.00781
RPL35 ribosomal protein L35 -2.00463
BCLAF1 BCL2-associated transcription factor 1 -2.00082
NUP98 nucleoporin 98kDa -2.00076
LDLR low density lipoprotein receptor -2.00032