CRCGN015_MCF10A_48H:D03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description serotonin 11.11 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN015_MCF10A_48H:D03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FPGS folylpolyglutamate synthase 3.36662
TIAM1 T-cell lymphoma invasion and metastasis 1 3.20199
GATA2 GATA binding protein 2 2.75734
NOSIP nitric oxide synthase interacting protein 2.65605
SIRT3 sirtuin 3 2.62829
RIC8A RIC8 guanine nucleotide exchange factor A 2.24799
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 2.17611
RPP40 ribonuclease P/MRP 40kDa subunit 2.17515
EPN2 epsin 2 2.17507
ELAC2 elaC ribonuclease Z 2 2.09894

decreased expression

Symbol Name Standardized Value
TNIP1 TNFAIP3 interacting protein 1 -3.45368
FBXO21 F-box protein 21 -3.09108
NUSAP1 nucleolar and spindle associated protein 1 -3.00502
PLS1 plastin 1 -2.9314
KRT14 keratin 14, type I -2.92695
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.44951
ZMIZ1 zinc finger, MIZ-type containing 1 -2.0792
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -2.05478