CRCGN015_MCF10A_48H:D05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description fm550 perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN015_MCF10A_48H:D05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP2K5 mitogen-activated protein kinase kinase 5 3.45637
STAP2 signal transducing adaptor family member 2 3.24697
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 3.21487
PDIA5 protein disulfide isomerase family A, member 5 3.09531
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.74302
TMED1 transmembrane emp24 protein transport domain containing 1 2.40654
ZNF589 zinc finger protein 589 2.34325
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.19236
WIF1 WNT inhibitory factor 1 2.12908
SRFBP1 serum response factor binding protein 1 2.1003

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -3.36571
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.96492
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.69646
MACF1 microtubule-actin crosslinking factor 1 -2.59591
VIM vimentin -2.551
MT2A metallothionein 2A -2.35058
EXT1 exostosin glycosyltransferase 1 -2.2744
DNAAF5 dynein, axonemal, assembly factor 5 -2.2167
PLK2 polo-like kinase 2 -2.16089