CRCGN015_MCF10A_48H:D09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,4-dinitrotoluene 11.11 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN015_MCF10A_48H:D09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 2.97447
PRKCQ protein kinase C, theta 2.70517
MAMLD1 mastermind-like domain containing 1 2.50261
ITK IL2-inducible T-cell kinase 2.39771
ALDOC aldolase C, fructose-bisphosphate 2.39229
ZNF589 zinc finger protein 589 2.2576
GPR171 G protein-coupled receptor 171 2.24775
NLRP2B NLR family pyrin domain containing 2B 2.07794
TRAPPC4 trafficking protein particle complex 4 2.07049
TUBG1 tubulin, gamma 1 2.05106

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -4.01989
PUF60 poly-U binding splicing factor 60KDa -3.73753
KRT7 keratin 7, type II -3.46737
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.87418
SCRIB scribbled planar cell polarity protein -2.54864
KRT14 keratin 14, type I -2.52586
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -2.35638
VIM vimentin -2.29566
HMG20B high mobility group 20B -2.12209
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 -2.02836