CRCGN015_MCF10A_48H:D14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,1,1-trichloroethane, technical grade 32.81 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN015_MCF10A_48H:D14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PRKCH protein kinase C, eta 3.39927
LAGE3 L antigen family, member 3 3.31674
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 3.06877
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 2.82524
ANO10 anoctamin 10 2.65028
ZNF589 zinc finger protein 589 2.63233
TSEN2 TSEN2 tRNA splicing endonuclease subunit 2.00166

decreased expression

Symbol Name Standardized Value
BAG3 BCL2-associated athanogene 3 -6.57131
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -6.2261
S100A8 S100 calcium binding protein A8 -4.50035
KRT14 keratin 14, type I -3.79893
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.29941
SNX7 sorting nexin 7 -2.34718
ATG4A autophagy related 4A, cysteine peptidase -2.05311