CRCGN015_MCF10A_48H:D15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,1,1-trichloroethane, technical grade 10.94 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN015_MCF10A_48H:D15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNX11 sorting nexin 11 2.88008
METRN meteorin, glial cell differentiation regulator 2.59239
PDIA5 protein disulfide isomerase family A, member 5 2.36715
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.14199
C2CD2 C2 calcium-dependent domain containing 2 2.07156
TARBP2 TAR (HIV-1) RNA binding protein 2 2.03783

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -3.75698
PCCB propionyl CoA carboxylase, beta polypeptide -3.51048
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -3.26713
JMJD6 jumonji domain containing 6 -2.6349
VIM vimentin -2.51834
GRN granulin -2.37805
STAT1 signal transducer and activator of transcription 1, 91kDa -2.33185
ATG3 autophagy related 3 -2.18724
KRT7 keratin 7, type II -2.06801