CRCGN015_MCF10A_48H:D17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-butyl chloride 34.33 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN015_MCF10A_48H:D17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HYOU1 hypoxia up-regulated 1 3.61053
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.37388
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.77715
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.09457
RPS5 ribosomal protein S5 2.07904
GTF2A2 general transcription factor IIA, 2, 12kDa 2.02072
TRAPPC4 trafficking protein particle complex 4 2.00765

decreased expression

Symbol Name Standardized Value
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -3.19877
CD44 CD44 molecule (Indian blood group) -2.7184
KRT14 keratin 14, type I -2.51814
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.18462
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.15631
RND3 Rho family GTPase 3 -2.05195
RNF43 ring finger protein 43 -2.02334