CRCGN015_MCF10A_48H:D19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description coumophos 97.26 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

43 genes differentially expressed following the CRCGN015_MCF10A_48H:D19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ACAA1 acetyl-CoA acyltransferase 1 3.77491
RAB31 RAB31, member RAS oncogene family 3.51775
CXCL2 chemokine (C-X-C motif) ligand 2 3.07973
HBA1 hemoglobin, alpha 1 2.80324
CXCL3 chemokine (C-X-C motif) ligand 3 2.43614
ILK integrin-linked kinase 2.4318
HMGA2 high mobility group AT-hook 2 2.43166
DUSP6 dual specificity phosphatase 6 2.39851
WIF1 WNT inhibitory factor 1 2.3869

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -6.91213
ENOPH1 enolase-phosphatase 1 -4.85651
S100A8 S100 calcium binding protein A8 -3.94673
SCYL3 SCY1-like 3 (S. cerevisiae) -2.74957
TBC1D31 TBC1 domain family, member 31 -2.60058
TSC22D3 TSC22 domain family, member 3 -2.5817
PRR15L proline rich 15-like -2.56699
ZFP30 ZFP30 zinc finger protein -2.38693
UNKL unkempt family zinc finger-like -2.36257
FAT4 FAT atypical cadherin 4 -2.2871
RRP1B ribosomal RNA processing 1B -2.25312
TTC27 tetratricopeptide repeat domain 27 -2.23871
BMPR1A bone morphogenetic protein receptor, type IA -2.2353
TEX10 testis expressed 10 -2.22519
ZFP37 ZFP37 zinc finger protein -2.21853
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 -2.21019
GTF2A1 general transcription factor IIA, 1, 19/37kDa -2.20879
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 -2.20442
APLNR apelin receptor -2.19427
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) -2.18072
ELOVL6 ELOVL fatty acid elongase 6 -2.17303
ADPRH ADP-ribosylarginine hydrolase -2.11635
BPIFA1 BPI fold containing family A, member 1 -2.11262
ENTR1 endosome associated trafficking regulator 1 -2.09343
EDA2R ectodysplasin A2 receptor -2.08136
ELP4 elongator acetyltransferase complex subunit 4 -2.07111
CERS1 ceramide synthase 1 -2.05029
RPAP2 RNA polymerase II associated protein 2 -2.04352
TMEM184C transmembrane protein 184C -2.0415
RPL39L ribosomal protein L39-like -2.02214
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 -2.02054
FAM13A family with sequence similarity 13, member A -2.01856
BLTP1 bridge-like lipid transfer protein family member 1 -2.01763
KRT14 keratin 14, type I -2.01141