| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | coumophos 32.42 um perturbation at 48 h in MCF10A (Carcinogenome) |
| Similar Terms | |
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125 genes differentially expressed following the CRCGN015_MCF10A_48H:D20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BAX | BCL2-associated X protein | 3.80853 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 3.62885 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | 3.17595 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.14033 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | 3.06156 |
| CCNJ | cyclin J | 3.06118 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 2.96746 |
| IREB2 | iron-responsive element binding protein 2 | 2.89048 |
| TRIB3 | tribbles pseudokinase 3 | 2.70098 |
| ATF4 | activating transcription factor 4 | 2.64387 |
| CORO1A | coronin, actin binding protein, 1A | 2.55439 |
| CD1D | CD1d molecule | 2.53728 |
| SMN2 | survival of motor neuron 2, centromeric | 2.53196 |
| CEP57 | centrosomal protein 57kDa | 2.48142 |
| BBS7 | Bardet-Biedl syndrome 7 | 2.44766 |
| IL15 | interleukin 15 | 2.4473 |
| GPALPP1 | GPALPP motifs containing 1 | 2.42899 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 2.40573 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa | 2.37873 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) | 2.37696 |
| WDHD1 | WD repeat and HMG-box DNA binding protein 1 | 2.35135 |
| MMP3 | matrix metallopeptidase 3 | 2.3466 |
| HKDC1 | hexokinase domain containing 1 | 2.32731 |
| ANKRD49 | ankyrin repeat domain 49 | 2.31803 |
| SKA1 | spindle and kinetochore associated complex subunit 1 | 2.31011 |
| ZMAT5 | zinc finger, matrin-type 5 | 2.30871 |
| SLC5A1 | solute carrier family 5 (sodium/glucose cotransporter), member 1 | 2.29638 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 2.28768 |
| CNTN1 | contactin 1 | 2.27779 |
| HIKESHI | heat shock protein nuclear import factor hikeshi | 2.27591 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 2.26279 |
| EXOSC5 | exosome component 5 | 2.2395 |
| DCHS1 | dachsous cadherin-related 1 | 2.2251 |
| PDIA2 | protein disulfide isomerase family A, member 2 | 2.22319 |
| MMP10 | matrix metallopeptidase 10 | 2.21553 |
| HAUS6 | HAUS augmin-like complex, subunit 6 | 2.20747 |
| KAT6B | K(lysine) acetyltransferase 6B | 2.20507 |
| ATXN7L1 | ataxin 7-like 1 | 2.19886 |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa | 2.19061 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 2.18782 |
| MFAP2 | microfibrillar-associated protein 2 | 2.16734 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 2.16669 |
| LOXL1 | lysyl oxidase-like 1 | 2.16414 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | 2.16037 |
| E2F8 | E2F transcription factor 8 | 2.14105 |
| APH1A | APH1A gamma secretase subunit | 2.14022 |
| JOSD1 | Josephin domain containing 1 | 2.12645 |
| CPOX | coproporphyrinogen oxidase | 2.11491 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 2.11089 |
| TNFAIP8L2-SCNM1 | TNFAIP8L2-SCNM1 readthrough | 2.10703 |
| SART1 | squamous cell carcinoma antigen recognized by T cells | 2.09316 |
| PRPF19 | pre-mRNA processing factor 19 | 2.09065 |
| STIL | SCL/TAL1 interrupting locus | 2.08265 |
| HSPA2 | heat shock 70kDa protein 2 | 2.08083 |
| SARS1 | seryl-tRNA synthetase 1 | 2.07738 |
| CBY1 | chibby homolog 1 (Drosophila) | 2.06874 |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 2.06692 |
| CHN1 | chimerin 1 | 2.05282 |
| GATAD2A | GATA zinc finger domain containing 2A | 2.02518 |
| RAB5C | RAB5C, member RAS oncogene family | 2.01026 |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa | 2.0098 |
| VPS37C | vacuolar protein sorting 37 homolog C (S. cerevisiae) | 2.00871 |
| FCRLB | Fc receptor-like B | 2.00841 |
| RGS20 | regulator of G-protein signaling 20 | 2.00136 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 2.00056 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -5.29522 |
| VDAC1 | voltage-dependent anion channel 1 | -5.20827 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -5.20298 |
| GNAS | GNAS complex locus | -4.06631 |
| MT2A | metallothionein 2A | -3.67421 |
| NELFCD | negative elongation factor complex member C/D | -3.38827 |
| ISOC1 | isochorismatase domain containing 1 | -3.28518 |
| PWP1 | PWP1 homolog (S. cerevisiae) | -3.21106 |
| GPR171 | G protein-coupled receptor 171 | -3.12969 |
| MSMO1 | methylsterol monooxygenase 1 | -2.99368 |
| MORC4 | MORC family CW-type zinc finger 4 | -2.98722 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -2.95515 |
| RPN2 | ribophorin II | -2.85379 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -2.77816 |
| DENR | density-regulated protein | -2.67222 |
| TDG | thymine-DNA glycosylase | -2.63464 |
| S100A8 | S100 calcium binding protein A8 | -2.60644 |
| PPARG | peroxisome proliferator-activated receptor gamma | -2.60089 |
| MOK | MOK protein kinase | -2.5794 |
| CCSER2 | coiled-coil serine-rich protein 2 | -2.56505 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -2.56143 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -2.5519 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) | -2.5184 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -2.49155 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -2.44091 |
| LEMD3 | LEM domain containing 3 | -2.39819 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | -2.3954 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | -2.39387 |
| TEX10 | testis expressed 10 | -2.34191 |
| PHF20L1 | PHD finger protein 20-like 1 | -2.29833 |
| CRY1 | cryptochrome circadian clock 1 | -2.26666 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 | -2.25118 |
| NDRG3 | NDRG family member 3 | -2.24161 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | -2.21453 |
| AHCY | adenosylhomocysteinase | -2.21221 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -2.18466 |
| TENT5A | terminal nucleotidyltransferase 5A | -2.17248 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | -2.17098 |
| UFSP2 | UFM1-specific peptidase 2 | -2.16085 |
| KLRC4-KLRK1 | KLRC4-KLRK1 readthrough | -2.15647 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -2.13599 |
| NTM | neurotrimin | -2.10244 |
| SMYD3 | SET and MYND domain containing 3 | -2.10054 |
| CHPT1 | choline phosphotransferase 1 | -2.09869 |
| TSPYL4 | TSPY-like 4 | -2.09611 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -2.0914 |
| NUP205 | nucleoporin 205kDa | -2.07986 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -2.06785 |
| CTSL | cathepsin L | -2.05511 |
| MPV17L-BMERB1 | MPV17L-BMERB1 readthrough | -2.05422 |
| ANKRD10 | ankyrin repeat domain 10 | -2.04738 |
| SLC35A1 | solute carrier family 35 (CMP-sialic acid transporter), member A1 | -2.04694 |
| CD96 | CD96 molecule | -2.04628 |
| S100A10 | S100 calcium binding protein A10 | -2.03734 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -2.03643 |
| DMBT1 | deleted in malignant brain tumors 1 | -2.02804 |
| ACY1 | aminoacylase 1 | -2.0192 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -2.0089 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -2.00512 |
| LOC122539214 | Zinc finger protein LOC122539214 | -2.00403 |
