CRCGN015_MCF10A_48H:D22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n,n-dimethyl-n'-[3-(trifluoromethyl)phenyl]urea 96.55 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN015_MCF10A_48H:D22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FKBP14 FK506 binding protein 14, 22 kDa 3.43919
E2F2 E2F transcription factor 2 3.08607
PRR7 proline rich 7 (synaptic) 2.47166
HDGFL3 HDGF like 3 2.22483
HBA1 hemoglobin, alpha 1 2.15637
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 2.12835

decreased expression

Symbol Name Standardized Value
HEATR1 HEAT repeat containing 1 -4.65969
FOXJ3 forkhead box J3 -3.44116
MSMO1 methylsterol monooxygenase 1 -3.38501
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.2987
KRT14 keratin 14, type I -3.25092
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -2.60259
STXBP2 syntaxin binding protein 2 -2.5802
ATG4A autophagy related 4A, cysteine peptidase -2.26776
MVP major vault protein -2.25712
REEP1 receptor accessory protein 1 -2.25004
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide -2.20526
OAT ornithine aminotransferase -2.11374
JAK1 Janus kinase 1 -2.05287
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 -2.04446