| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tin (ii) chloride 33.32 um perturbation at 48 h in MCF10A (Carcinogenome) |
| Similar Terms | |
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140 genes differentially expressed following the CRCGN015_MCF10A_48H:E02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 9.64473 |
| SCRN1 | secernin 1 | 4.878 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 4.11465 |
| STAP2 | signal transducing adaptor family member 2 | 3.6928 |
| HEATR6 | HEAT repeat containing 6 | 3.54517 |
| LSR | lipolysis stimulated lipoprotein receptor | 3.3618 |
| HYOU1 | hypoxia up-regulated 1 | 3.22615 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 3.19345 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 3.06813 |
| TUBD1 | tubulin, delta 1 | 3.01817 |
| PAX6 | paired box 6 | 3.0105 |
| CBX1 | chromobox homolog 1 | 2.9688 |
| LRRC59 | leucine rich repeat containing 59 | 2.9632 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 2.87418 |
| SNX11 | sorting nexin 11 | 2.85427 |
| HELZ | helicase with zinc finger | 2.83805 |
| NUP205 | nucleoporin 205kDa | 2.8342 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.8108 |
| HAVCR1 | hepatitis A virus cellular receptor 1 | 2.76485 |
| ZNF750 | zinc finger protein 750 | 2.70745 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 2.64295 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 | 2.63345 |
| GADD45GIP1 | growth arrest and DNA-damage-inducible, gamma interacting protein 1 | 2.5718 |
| BCAS3 | breast carcinoma amplified sequence 3 | 2.56955 |
| CASC3 | cancer susceptibility candidate 3 | 2.55615 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 | 2.5531 |
| FZD1 | frizzled class receptor 1 | 2.55062 |
| KRT6B | keratin 6B, type II | 2.5273 |
| B3GAT3 | beta-1,3-glucuronyltransferase 3 | 2.51297 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 2.50445 |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | 2.4522 |
| USP18 | ubiquitin specific peptidase 18 | 2.4426 |
| TUBGCP4 | tubulin, gamma complex associated protein 4 | 2.43845 |
| PERP | PERP, TP53 apoptosis effector | 2.4336 |
| LRRC8E | leucine rich repeat containing 8 family, member E | 2.4323 |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 2.41475 |
| FN3KRP | fructosamine 3 kinase related protein | 2.3771 |
| MEN1 | multiple endocrine neoplasia I | 2.37305 |
| TMED1 | transmembrane emp24 protein transport domain containing 1 | 2.3637 |
| HYAL2 | hyaluronoglucosaminidase 2 | 2.3314 |
| ZKSCAN2 | zinc finger with KRAB and SCAN domains 2 | 2.33025 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | 2.3104 |
| COBL | cordon-bleu WH2 repeat protein | 2.2907 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 2.26025 |
| BOLA1 | bolA family member 1 | 2.23905 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 2.23105 |
| MTMR4 | myotubularin related protein 4 | 2.22835 |
| PHB1 | prohibitin 1 | 2.2234 |
| APOLD1 | apolipoprotein L domain containing 1 | 2.2077 |
| EMC7 | ER membrane protein complex subunit 7 | 2.1864 |
| PI15 | peptidase inhibitor 15 | 2.1858 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 2.18525 |
| GET3 | guided entry of tail-anchored proteins factor 3, ATPase | 2.17335 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) | 2.15245 |
| CLDND1 | claudin domain containing 1 | 2.1456 |
| TPD52L1 | tumor protein D52-like 1 | 2.1453 |
| IFT46 | intraflagellar transport 46 | 2.1406 |
| EPN2 | epsin 2 | 2.13 |
| MPV17 | MpV17 mitochondrial inner membrane protein | 2.123 |
| MED13 | mediator complex subunit 13 | 2.12165 |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) | 2.0942 |
| NFX1 | nuclear transcription factor, X-box binding 1 | 2.08915 |
| OCRL | oculocerebrorenal syndrome of Lowe | 2.0891 |
| FAM184A | family with sequence similarity 184, member A | 2.08895 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 | 2.0777 |
| ARB2A | ARB2 cotranscriptional regulator A | 2.07 |
| ATP5MC1 | ATP synthase membrane subunit c locus 1 | 2.0663 |
| SERINC1 | serine incorporator 1 | 2.0643 |
| DAPK2 | death-associated protein kinase 2 | 2.05483 |
| NDUFC1 | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa | 2.03435 |
| CD320 | CD320 molecule | 2.0225 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 2.0037 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -7.12065 |
| SLC35F2 | solute carrier family 35, member F2 | -5.9613 |
| TXNDC9 | thioredoxin domain containing 9 | -5.17855 |
| CAB39 | calcium binding protein 39 | -4.50905 |
| GRN | granulin | -4.2586 |
| CDC20 | cell division cycle 20 | -3.8312 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -3.73583 |
| STARD7 | StAR-related lipid transfer (START) domain containing 7 | -3.43835 |
| LIPT1 | lipoyltransferase 1 | -3.2732 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -3.19198 |
| MT1X | metallothionein 1X | -3.04315 |
| CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 | -2.82325 |
| LINC02762 | long intergenic non-protein coding RNA 2762 | -2.7791 |
| ACTR1B | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) | -2.77055 |
| TMEM127 | transmembrane protein 127 | -2.76035 |
| TMEM131 | transmembrane protein 131 | -2.703 |
| OSBPL9 | oxysterol binding protein-like 9 | -2.641 |
| AOX1 | aldehyde oxidase 1 | -2.5963 |
| EIF5B | eukaryotic translation initiation factor 5B | -2.56052 |
| LMAN2L | lectin, mannose-binding 2-like | -2.5478 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -2.526 |
| UXS1 | UDP-glucuronate decarboxylase 1 | -2.5249 |
| PANK2 | pantothenate kinase 2 | -2.51415 |
| ATIC | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase | -2.44065 |
| AIMP2 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 | -2.43675 |
| RB1 | retinoblastoma 1 | -2.4288 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa | -2.4151 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | -2.36635 |
| KIAA0232 | KIAA0232 | -2.336 |
| MLH1 | mutL homolog 1 | -2.31135 |
| DGKH | diacylglycerol kinase, eta | -2.28215 |
| INTS11 | integrator complex subunit 11 | -2.27295 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -2.25225 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -2.19745 |
| HAMP | hepcidin antimicrobial peptide | -2.1944 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | -2.19025 |
| SMPD4 | sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) | -2.18325 |
| MT1H | metallothionein 1H | -2.17702 |
| UNC50 | unc-50 homolog (C. elegans) | -2.1765 |
| ALG11 | ALG11, alpha-1,2-mannosyltransferase | -2.17305 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 | -2.17075 |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase | -2.16988 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 | -2.15465 |
| CYRIA | CYFIP related Rac1 interactor A | -2.14703 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -2.14603 |
| KLF10 | Kruppel-like factor 10 | -2.12865 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 | -2.1152 |
| REV1 | REV1, polymerase (DNA directed) | -2.10035 |
| RPN1 | ribophorin I | -2.0955 |
| RWDD3 | RWD domain containing 3 | -2.09445 |
| PCBP3 | poly(rC) binding protein 3 | -2.09065 |
| FSTL1 | follistatin-like 1 | -2.0885 |
| PDCL3 | phosducin-like 3 | -2.0675 |
| OLFM4 | olfactomedin 4 | -2.066 |
| WBP4 | WW domain binding protein 4 | -2.06307 |
| FXYD7 | FXYD domain containing ion transport regulator 7 | -2.06245 |
| TMEM100 | transmembrane protein 100 | -2.0531 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -2.05015 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -2.03575 |
| MXRA5 | matrix-remodelling associated 5 | -2.0303 |
| STIL | SCL/TAL1 interrupting locus | -2.0289 |
| QARS1 | glutaminyl-tRNA synthetase 1 | -2.02355 |
| RETN | resistin | -2.0227 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | -2.0219 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | -2.01275 |
| RAB20 | RAB20, member RAS oncogene family | -2.0118 |
| SETD4 | SET domain containing 4 | -2.0107 |
| MMADHC | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria | -2.00735 |
