CRCGN015_MCF10A_48H:E03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tin (ii) chloride 11.11 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN015_MCF10A_48H:E03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MYLK myosin light chain kinase 4.86597
GRWD1 glutamate-rich WD repeat containing 1 4.69258
ADGRE5 adhesion G protein-coupled receptor E5 4.31051
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.32617
PDIA5 protein disulfide isomerase family A, member 5 2.94577
HBA1 hemoglobin, alpha 1 2.79986
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.77574
PYCR1 pyrroline-5-carboxylate reductase 1 2.56921
IPO4 importin 4 2.20903
MAPK9 mitogen-activated protein kinase 9 2.15264
PCM1 pericentriolar material 1 2.11822
ZNF574 zinc finger protein 574 2.03683

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -5.18138
MT2A metallothionein 2A -4.66901
MT1X metallothionein 1X -4.06894
TNIP1 TNFAIP3 interacting protein 1 -3.43473
RBM34 RNA binding motif protein 34 -3.31741
TUBG2 tubulin, gamma 2 -2.36518
ATP11B ATPase, class VI, type 11B -2.28648
GLOD4 glyoxalase domain containing 4 -2.15202
CIRSR corepressor of RBPJ and splicing regulator -2.13462
VPS9D1 VPS9 domain containing 1 -2.13186
KRT7 keratin 7, type II -2.09786
CCDC90B coiled-coil domain containing 90B -2.09786
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 -2.05395