CRCGN015_MCF10A_48H:E04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tricresyl phosphate 100.97 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

30 genes differentially expressed following the CRCGN015_MCF10A_48H:E04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MEF2C myocyte enhancer factor 2C 3.66165
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.36985
MAP3K5 mitogen-activated protein kinase kinase kinase 5 2.19976
FZD1 frizzled class receptor 1 2.1559
MYBPC1 myosin binding protein C, slow type 2.11398
TAC4 tachykinin 4 (hemokinin) 2.09047
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 2.06417
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 2.04406

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -8.50949
PLS1 plastin 1 -6.58107
CAB39 calcium binding protein 39 -3.16685
CD24 CD24 molecule -2.97602
CDC20 cell division cycle 20 -2.89645
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.76981
SQLE squalene epoxidase -2.68456
ANXA3 annexin A3 -2.66867
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.65632
INSIG1 insulin induced gene 1 -2.37538
MYL9 myosin, light chain 9, regulatory -2.3087
CXCL2 chemokine (C-X-C motif) ligand 2 -2.30728
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.26258
TP53I3 tumor protein p53 inducible protein 3 -2.20288
GAS6 growth arrest-specific 6 -2.19917
SPAG1 sperm associated antigen 1 -2.12776
MELK maternal embryonic leucine zipper kinase -2.12436
MISP mitotic spindle positioning -2.08728
JADE3 jade family PHD finger 3 -2.06393
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -2.05779
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 -2.03603
RFTN1 raftlin, lipid raft linker 1 -2.00812