CRCGN015_MCF10A_48H:E10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4,4'-methylene-bis(2-methyl?aniline) 100.97 um perturbation at 48 h in MCF10A (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

53 genes differentially expressed following the CRCGN015_MCF10A_48H:E10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STIMATE STIM activating enhancer 5.06205
NUCB2 nucleobindin 2 4.1494
GARRE1 granule associated Rac and RHOG effector 1 3.9957
MAP2K5 mitogen-activated protein kinase kinase 5 3.83378
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 3.0636
TGFB3 transforming growth factor, beta 3 2.88145
CCNA1 cyclin A1 2.7947
PARP16 poly (ADP-ribose) polymerase family, member 16 2.6741
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.62035
CHEK2 checkpoint kinase 2 2.44565
VAT1 vesicle amine transport 1 2.3926
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.35275
ENOX2 ecto-NOX disulfide-thiol exchanger 2 2.25568
RAB4B RAB4B, member RAS oncogene family 2.22425
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 2.21305
LRRC15 leucine rich repeat containing 15 2.21185
LIMK2 LIM domain kinase 2 2.1357
NDN necdin, melanoma antigen (MAGE) family member 2.1349
ACOT8 acyl-CoA thioesterase 8 2.1318
KCTD15 potassium channel tetramerization domain containing 15 2.12555
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like 2.11385
PRKX protein kinase, X-linked 2.10775
SARS1 seryl-tRNA synthetase 1 2.062
GFPT1 glutamine--fructose-6-phosphate transaminase 1 2.06047
MID2 midline 2 2.06032
MXRA5 matrix-remodelling associated 5 2.0525
PRELID3A PRELI domain containing 3A 2.044
STEAP1B STEAP family member 1B 2.01035

decreased expression

Symbol Name Standardized Value
NPDC1 neural proliferation, differentiation and control, 1 -4.9765
CREG1 cellular repressor of E1A-stimulated genes 1 -3.68295
CIAPIN1 cytokine induced apoptosis inhibitor 1 -3.23838
PLS1 plastin 1 -3.2101
MAP3K14 mitogen-activated protein kinase kinase kinase 14 -2.95165
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -2.60985
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 -2.60365
DUSP14 dual specificity phosphatase 14 -2.5804
ANXA3 annexin A3 -2.55415
IFI44L interferon-induced protein 44-like -2.33475
TESC tescalcin -2.29325
DCLRE1C DNA cross-link repair 1C -2.29
RUVBL1 RuvB-like AAA ATPase 1 -2.2585
IPO4 importin 4 -2.18075
RUNX3 runt-related transcription factor 3 -2.16307
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -2.1198
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -2.0973
TLR6 toll-like receptor 6 -2.0889
ASCC3 activating signal cointegrator 1 complex subunit 3 -2.06195
HSPA14 heat shock 70kDa protein 14 -2.05945
SH3GL1 SH3-domain GRB2-like 1 -2.0319
HSPB8 heat shock 22kDa protein 8 -2.0193
CNOT2 CCR4-NOT transcription complex, subunit 2 -2.01237
CASC3 cancer susceptibility candidate 3 -2.01125
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa -2.0036