| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | bisphenol-a 11.11 um perturbation at 48 h in MCF10A (Carcinogenome) |
| Similar Terms | |
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216 genes differentially expressed following the CRCGN015_MCF10A_48H:E15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PRKCQ | protein kinase C, theta | 5.25029 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.66826 |
| NOSIP | nitric oxide synthase interacting protein | 3.46692 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 3.41365 |
| GPR20 | G protein-coupled receptor 20 | 3.394 |
| CENPX | centromere protein X | 3.11834 |
| CSK | c-src tyrosine kinase | 3.10286 |
| PTCD2 | pentatricopeptide repeat domain 2 | 2.95145 |
| PPCDC | phosphopantothenoylcysteine decarboxylase | 2.9189 |
| TBCCD1 | TBCC domain containing 1 | 2.91525 |
| PRKX | protein kinase, X-linked | 2.90427 |
| PRMT7 | protein arginine methyltransferase 7 | 2.89436 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 | 2.89118 |
| SMN2 | survival of motor neuron 2, centromeric | 2.80106 |
| ENOSF1 | enolase superfamily member 1 | 2.7991 |
| IL32 | interleukin 32 | 2.78271 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.72194 |
| INTS3 | integrator complex subunit 3 | 2.72032 |
| MFAP2 | microfibrillar-associated protein 2 | 2.72004 |
| CCKBR | cholecystokinin B receptor | 2.68758 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | 2.63134 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 2.61889 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 2.57778 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 2.44921 |
| RAB17 | RAB17, member RAS oncogene family | 2.4453 |
| BEX3 | brain expressed X-linked 3 | 2.43374 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 2.42096 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 2.41998 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 2.4051 |
| THBD | thrombomodulin | 2.40063 |
| SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 | 2.39573 |
| FYB1 | FYN binding protein 1 | 2.39362 |
| THAP1 | THAP domain containing, apoptosis associated protein 1 | 2.38445 |
| C1QA | complement component 1, q subcomponent, A chain | 2.37855 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 | 2.37495 |
| AVIL | advillin | 2.37326 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 2.37156 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 | 2.34871 |
| FGL2 | fibrinogen-like 2 | 2.34381 |
| TBCC | tubulin folding cofactor C | 2.33626 |
| BNC2 | basonuclin 2 | 2.33127 |
| TPBG | trophoblast glycoprotein | 2.32148 |
| CCDC170 | coiled-coil domain containing 170 | 2.31917 |
| TACO1 | translational activator of mitochondrially encoded cytochrome c oxidase I | 2.30362 |
| DTWD1 | DTW domain containing 1 | 2.30313 |
| ICE2 | interactor of little elongation complex ELL subunit 2 | 2.3026 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 2.29848 |
| COX11 | COX11 cytochrome c oxidase copper chaperone | 2.28884 |
| CD1B | CD1b molecule | 2.28168 |
| THUMPD2 | THUMP domain containing 2 | 2.27871 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 2.27198 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 2.25032 |
| CCNL2 | cyclin L2 | 2.24846 |
| RPAIN | RPA interacting protein | 2.24817 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 | 2.24439 |
| ANAPC10 | anaphase promoting complex subunit 10 | 2.24389 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 2.23156 |
| COL18A1 | collagen, type XVIII, alpha 1 | 2.23139 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | 2.22503 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 | 2.22342 |
| CD96 | CD96 molecule | 2.21273 |
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 2.20519 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 2.2049 |
| KAT2A | K(lysine) acetyltransferase 2A | 2.2014 |
| CZIB | CXXC motif containing zinc binding protein | 2.20057 |
| DMWD | dystrophia myotonica, WD repeat containing | 2.19493 |
| EXOSC5 | exosome component 5 | 2.18709 |
| TBX21 | T-box 21 | 2.14932 |
| OBI1 | ORC ubiquitin ligase 1 | 2.14915 |
| PFN2 | profilin 2 | 2.1398 |
| GPN2 | GPN-loop GTPase 2 | 2.13928 |
| ITK | IL2-inducible T-cell kinase | 2.13606 |
| ETAA1 | Ewing tumor-associated antigen 1 | 2.13462 |
| LIME1 | Lck interacting transmembrane adaptor 1 | 2.13418 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 2.12593 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | 2.11888 |
| ANKMY2 | ankyrin repeat and MYND domain containing 2 | 2.10971 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 2.10802 |
| ATG5 | autophagy related 5 | 2.10725 |
| WDR73 | WD repeat domain 73 | 2.10678 |
| EVI2A | ecotropic viral integration site 2A | 2.1003 |
| RASIP1 | Ras interacting protein 1 | 2.09931 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | 2.09857 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | 2.09731 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | 2.07893 |
| BCCIP | BRCA2 and CDKN1A interacting protein | 2.06525 |
| AATF | apoptosis antagonizing transcription factor | 2.06227 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma | 2.06161 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 | 2.04979 |
| KIF18B | kinesin family member 18B | 2.04575 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | 2.0428 |
| MANEA | mannosidase, endo-alpha | 2.04237 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 2.03077 |
| PSAT1 | phosphoserine aminotransferase 1 | 2.02979 |
| KAT2B | K(lysine) acetyltransferase 2B | 2.02004 |
| SUPT4H1 | suppressor of Ty 4 homolog 1 (S. cerevisiae) | 2.02002 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa | 2.01883 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 2.01866 |
| PSMC3IP | PSMC3 interacting protein | 2.01742 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 2.01457 |
| TIMM44 | translocase of inner mitochondrial membrane 44 homolog (yeast) | 2.01457 |
| LY96 | lymphocyte antigen 96 | 2.00717 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 2.00711 |
| NUBP2 | nucleotide binding protein 2 | 2.00126 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -5.42011 |
| HSPA1A | heat shock 70kDa protein 1A | -5.38381 |
| VIM | vimentin | -4.85582 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial | -4.85446 |
| DNM1L | dynamin 1-like | -4.685 |
| YME1L1 | YME1-like 1 ATPase | -4.6797 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -4.38431 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -4.337 |
| SLC35F2 | solute carrier family 35, member F2 | -4.30602 |
| GNAS | GNAS complex locus | -3.79781 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.79676 |
| IDH3B | isocitrate dehydrogenase 3 (NAD+) beta | -3.77202 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.53342 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -3.51136 |
| MSMO1 | methylsterol monooxygenase 1 | -3.49748 |
| UXS1 | UDP-glucuronate decarboxylase 1 | -3.48839 |
| NENF | neudesin neurotrophic factor | -3.45114 |
| KRT14 | keratin 14, type I | -3.40526 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | -3.39379 |
| FKBP1C | FK506 binding protein 1C | -3.32292 |
| HMG20B | high mobility group 20B | -3.29437 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -3.29292 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -3.27079 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -3.24541 |
| LDHB | lactate dehydrogenase B | -3.20742 |
| NELFCD | negative elongation factor complex member C/D | -3.03772 |
| ABI1 | abl-interactor 1 | -3.03583 |
| SNX5 | sorting nexin 5 | -2.89735 |
| PANK2 | pantothenate kinase 2 | -2.88582 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -2.84408 |
| SINHCAF | SIN3-HDAC complex associated factor | -2.82687 |
| ATG3 | autophagy related 3 | -2.82086 |
| WASHC4 | WASH complex subunit 4 | -2.79899 |
| HEATR1 | HEAT repeat containing 1 | -2.79832 |
| PRNP | prion protein | -2.79188 |
| PLK3 | polo-like kinase 3 | -2.75053 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) | -2.7095 |
| ERGIC2 | ERGIC and golgi 2 | -2.64164 |
| HSPA1B | heat shock 70kDa protein 1B | -2.63454 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -2.60405 |
| KRT7 | keratin 7, type II | -2.59995 |
| ATP9A | ATPase, class II, type 9A | -2.59573 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.58735 |
| OTUD3 | OTU deubiquitinase 3 | -2.57238 |
| DDRGK1 | DDRGK domain containing 1 | -2.56947 |
| PCDH9 | protocadherin 9 | -2.55536 |
| BMS1 | BMS1 ribosome biogenesis factor | -2.53673 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | -2.5351 |
| CRNKL1 | crooked neck pre-mRNA splicing factor 1 | -2.51795 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -2.50871 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | -2.48378 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -2.45656 |
| KIF5B | kinesin family member 5B | -2.4441 |
| CTPS1 | CTP synthase 1 | -2.42963 |
| TXNRD3 | thioredoxin reductase 3 | -2.4233 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -2.40442 |
| FRMD4B | FERM domain containing 4B | -2.35674 |
| APH1B | APH1B gamma secretase subunit | -2.33173 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | -2.32291 |
| TUBA1C | tubulin, alpha 1c | -2.32216 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -2.31385 |
| ROPN1B | rhophilin associated tail protein 1B | -2.31165 |
| RPN2 | ribophorin II | -2.3115 |
| OAT | ornithine aminotransferase | -2.3013 |
| FKBP6 | FK506 binding protein 6, 36kDa | -2.29207 |
| RAN | RAN, member RAS oncogene family | -2.28271 |
| CCL21 | chemokine (C-C motif) ligand 21 | -2.28085 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -2.26934 |
| PYGB | phosphorylase, glycogen; brain | -2.26784 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -2.26254 |
| ACOT2 | acyl-CoA thioesterase 2 | -2.25065 |
| PIGV | phosphatidylinositol glycan anchor biosynthesis, class V | -2.22764 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -2.22676 |
| GLOD4 | glyoxalase domain containing 4 | -2.22306 |
| WAC | WW domain containing adaptor with coiled-coil | -2.21385 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.20853 |
| CENPU | centromere protein U | -2.20044 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | -2.19568 |
| H2AZ1 | H2A.Z variant histone 1 | -2.18005 |
| HDAC7 | histone deacetylase 7 | -2.17903 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 | -2.17147 |
| LOC114841035 | uncharacterized LOC114841035 | -2.1699 |
| CALML5 | calmodulin-like 5 | -2.16899 |
| SCRN1 | secernin 1 | -2.16685 |
| KIF16B | kinesin family member 16B | -2.16417 |
| ATRN | attractin | -2.15701 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | -2.15609 |
| COX6A1 | cytochrome c oxidase subunit VIa polypeptide 1 | -2.15576 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 | -2.14008 |
| AACS | acetoacetyl-CoA synthetase | -2.133 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -2.12622 |
| MKKS | McKusick-Kaufman syndrome | -2.11367 |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) | -2.11282 |
| PLCB4 | phospholipase C, beta 4 | -2.11167 |
| TDRD7 | tudor domain containing 7 | -2.10965 |
| TFE3 | transcription factor binding to IGHM enhancer 3 | -2.10176 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -2.10038 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) | -2.09802 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -2.09797 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 | -2.0874 |
| KIN | Kin17 DNA and RNA binding protein | -2.07028 |
| PRPF18 | pre-mRNA processing factor 18 | -2.0643 |
| DENR | density-regulated protein | -2.05524 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | -2.05077 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | -2.04753 |
| MDH1 | malate dehydrogenase 1, NAD (soluble) | -2.04049 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | -2.0401 |
| CDC123 | cell division cycle 123 | -2.03542 |
| CHKA | choline kinase alpha | -2.0334 |
| PDCL3 | phosducin-like 3 | -2.02048 |
| TAOK3 | TAO kinase 3 | -2.00214 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 | -2.00112 |
