CRCGN015_MCF10A_48H:E18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description propyl gallate 11.16 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

13 genes differentially expressed following the CRCGN015_MCF10A_48H:E18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KDM5A lysine (K)-specific demethylase 5A 3.83025
SNX11 sorting nexin 11 2.79035
ZNF148 zinc finger protein 148 2.33601
CHEK2 checkpoint kinase 2 2.29464
GSK3B glycogen synthase kinase 3 beta 2.15218
RFX5 regulatory factor X, 5 (influences HLA class II expression) 2.04727

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -6.54503
PRPF4 pre-mRNA processing factor 4 -3.61199
PLK2 polo-like kinase 2 -2.8349
REEP5 receptor accessory protein 5 -2.64015
ANXA3 annexin A3 -2.34456
NPDC1 neural proliferation, differentiation and control, 1 -2.27554
TBC1D31 TBC1 domain family, member 31 -2.25137