| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n,n??=-diacetylbenzidine 102.27 um perturbation at 48 h in MCF10A (Carcinogenome) |
| Similar Terms | |
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111 genes differentially expressed following the CRCGN015_MCF10A_48H:E19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| WIF1 | WNT inhibitory factor 1 | 5.71483 |
| MYLK | myosin light chain kinase | 4.32827 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial | 3.37141 |
| AUNIP | aurora kinase A and ninein interacting protein | 3.23072 |
| ELAC2 | elaC ribonuclease Z 2 | 3.07188 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.05948 |
| ZW10 | zw10 kinetochore protein | 3.04524 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 2.79952 |
| IRS2 | insulin receptor substrate 2 | 2.76734 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.72577 |
| ATP5F1A | ATP synthase F1 subunit alpha | 2.66016 |
| ATP8B4 | ATPase, class I, type 8B, member 4 | 2.57915 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.56089 |
| ARRB2 | arrestin, beta 2 | 2.55556 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 2.49529 |
| NPTX2 | neuronal pentraxin II | 2.49364 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | 2.45048 |
| SRMS | src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites | 2.42919 |
| DLK1 | delta-like 1 homolog (Drosophila) | 2.37654 |
| IFFO1 | intermediate filament family orphan 1 | 2.36877 |
| ATXN10 | ataxin 10 | 2.34738 |
| ATAD5 | ATPase family, AAA domain containing 5 | 2.31517 |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 | 2.31041 |
| MEOX2 | mesenchyme homeobox 2 | 2.30835 |
| ACP3 | acid phosphatase 3 | 2.29916 |
| ZNF180 | zinc finger protein 180 | 2.25881 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa | 2.25816 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 2.22669 |
| BCS1L | BC1 (ubiquinol-cytochrome c reductase) synthesis-like | 2.22509 |
| FLT3 | fms-related tyrosine kinase 3 | 2.21492 |
| SYNGR1 | synaptogyrin 1 | 2.21162 |
| YBX1 | Y box binding protein 1 | 2.17651 |
| RPP25 | ribonuclease P/MRP 25kDa subunit | 2.16243 |
| FNDC4 | fibronectin type III domain containing 4 | 2.15983 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | 2.1598 |
| JMJD7 | jumonji domain containing 7 | 2.15787 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 2.13481 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 | 2.13377 |
| WDR45B | WD repeat domain 45B | 2.12026 |
| SCHIP1 | schwannomin interacting protein 1 | 2.11526 |
| ZIC1 | Zic family member 1 | 2.10737 |
| WRAP73 | WD repeat containing, antisense to TP73 | 2.09639 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N | 2.09028 |
| CD33 | CD33 molecule | 2.07777 |
| DOCK2 | dedicator of cytokinesis 2 | 2.06784 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 2.06548 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 | 2.05232 |
| NUBP2 | nucleotide binding protein 2 | 2.04978 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) | 2.0491 |
| PSAT1 | phosphoserine aminotransferase 1 | 2.04205 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | 2.03827 |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 | 2.03486 |
| STK32B | serine/threonine kinase 32B | 2.03041 |
| SCG2 | secretogranin II | 2.02709 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 2.02278 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 2.00733 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPA3 | replication protein A3, 14kDa | -8.47143 |
| DIPK1A | divergent protein kinase domain 1A | -7.84812 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -4.62719 |
| CCNB1 | cyclin B1 | -4.6049 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | -4.14574 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.94764 |
| STXBP2 | syntaxin binding protein 2 | -3.87073 |
| WASHC3 | WASH complex subunit 3 | -3.72414 |
| ZNF12 | zinc finger protein 12 | -3.70657 |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | -3.70458 |
| KRT14 | keratin 14, type I | -3.29767 |
| HMG20B | high mobility group 20B | -3.1671 |
| ZDHHC4 | zinc finger, DHHC-type containing 4 | -3.14838 |
| RSPH10B2 | radial spoke head 10 homolog B2 (Chlamydomonas) | -3.12056 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | -3.05497 |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) | -2.91848 |
| CYTH3 | cytohesin 3 | -2.89112 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.799 |
| RAD17 | RAD17 homolog (S. pombe) | -2.70749 |
| DNAAF5 | dynein, axonemal, assembly factor 5 | -2.66679 |
| COXFA4 | cytochrome c oxidase associated subunit FA4 | -2.63671 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -2.51221 |
| MSMO1 | methylsterol monooxygenase 1 | -2.41645 |
| PALLD | palladin, cytoskeletal associated protein | -2.40098 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -2.39657 |
| BCCIP | BRCA2 and CDKN1A interacting protein | -2.37772 |
| GIN1 | gypsy retrotransposon integrase 1 | -2.36715 |
| COX17 | COX17 cytochrome c oxidase copper chaperone | -2.34018 |
| AK6 | adenylate kinase 6 | -2.32435 |
| NFIL3 | nuclear factor, interleukin 3 regulated | -2.32241 |
| MRM2 | mitochondrial rRNA methyltransferase 2 | -2.32177 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | -2.29253 |
| ZBED5 | zinc finger, BED-type containing 5 | -2.25325 |
| AMZ2 | archaelysin family metallopeptidase 2 | -2.22202 |
| TMEM187 | transmembrane protein 187 | -2.21955 |
| SLC16A6 | solute carrier family 16, member 6 | -2.21171 |
| BORCS6 | BLOC-1 related complex subunit 6 | -2.20284 |
| IQCE | IQ motif containing E | -2.19863 |
| AIMP2 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 | -2.18473 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -2.15627 |
| CMC2 | C-x(9)-C motif containing 2 | -2.15526 |
| COX6A1 | cytochrome c oxidase subunit VIa polypeptide 1 | -2.14237 |
| TRADD | TNFRSF1A-associated via death domain | -2.14065 |
| PRSS8 | protease, serine, 8 | -2.10821 |
| SETD5 | SET domain containing 5 | -2.09917 |
| SLC28A2 | solute carrier family 28 (concentrative nucleoside transporter), member 2 | -2.09526 |
| COX7B | cytochrome c oxidase subunit VIIb | -2.0935 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 | -2.0899 |
| LOC107986346 | mitochondrial import receptor subunit TOM7 homolog | -2.08229 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -2.08009 |
| NDUFA7 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa | -2.07125 |
| TRMT61B | tRNA methyltransferase 61B | -2.06916 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | -2.02116 |
| AFTPH | aftiphilin | -2.01591 |
| SETD1A | SET domain containing 1A | -2.01083 |
