CRCGN015_MCF10A_48H:E23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description norethindrone 33.36 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN015_MCF10A_48H:E23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AXIN1 axin 1 4.7506
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.20896
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.375
MTA2 metastasis associated 1 family, member 2 2.07976
ZNF761 zinc finger protein 761 2.04462
ZNF211 zinc finger protein 211 2.02103
SH3BP1 SH3-domain binding protein 1 2.01464

decreased expression

Symbol Name Standardized Value
HEATR1 HEAT repeat containing 1 -4.27135
KRT14 keratin 14, type I -4.01001
VIM vimentin -3.22336
TBCE tubulin folding cofactor E -2.84085
TSC22D3 TSC22 domain family, member 3 -2.7296
GGPS1 geranylgeranyl diphosphate synthase 1 -2.45231
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.21146
RBM34 RNA binding motif protein 34 -2.14119
LOC124907782 dual specificity protein phosphatase 22 -2.12592
ZNF165 zinc finger protein 165 -2.08481