CRCGN015_MCF10A_48H:E24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description norethindrone 11.12 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN015_MCF10A_48H:E24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DLK1 delta-like 1 homolog (Drosophila) 3.11585
EPN2 epsin 2 3.01316
SSBP2 single-stranded DNA binding protein 2 2.85382
CCNA1 cyclin A1 2.81426
KLHL21 kelch-like family member 21 2.51647
NVL nuclear VCP-like 2.24652
FBXL12 F-box and leucine-rich repeat protein 12 2.06822
CORO1A coronin, actin binding protein, 1A 2.01826

decreased expression

Symbol Name Standardized Value
SLC25A46 solute carrier family 25, member 46 -4.18428
MT2A metallothionein 2A -3.61532
STAT1 signal transducer and activator of transcription 1, 91kDa -2.42421
ELL2 elongation factor, RNA polymerase II, 2 -2.11474
CZIB CXXC motif containing zinc binding protein -2.04609
TM9SF3 transmembrane 9 superfamily member 3 -2.00658