CRCGN015_MCF10A_48H:F03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description diethylstilbestrol 11.16 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

79 genes differentially expressed following the CRCGN015_MCF10A_48H:F03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MEF2C myocyte enhancer factor 2C 4.3883
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.93585
METRN meteorin, glial cell differentiation regulator 3.72615
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 2.68555
HEXB hexosaminidase B (beta polypeptide) 2.5268
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 2.43055
NUCB2 nucleobindin 2 2.4015
PYCR1 pyrroline-5-carboxylate reductase 1 2.3887
RBKS ribokinase 2.38723
TRAM2 translocation associated membrane protein 2 2.384
PDK4 pyruvate dehydrogenase kinase, isozyme 4 2.34085
NMRK1 nicotinamide riboside kinase 1 2.3356
SDF2L1 stromal cell-derived factor 2-like 1 2.1494
POLR2H polymerase (RNA) II (DNA directed) polypeptide H 2.1293
FXYD2 FXYD domain containing ion transport regulator 2 2.1244
GLDC glycine dehydrogenase (decarboxylating) 2.10695
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.1057
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 2.05925
MYDGF myeloid-derived growth factor 2.0506
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.04485

decreased expression

Symbol Name Standardized Value
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -10.0
MSMO1 methylsterol monooxygenase 1 -5.51365
TES testin LIM domain protein -5.27863
VIM vimentin -5.0
DCK deoxycytidine kinase -4.81775
GNAS GNAS complex locus -4.38268
CHD3 chromodomain helicase DNA binding protein 3 -3.65085
KRT14 keratin 14, type I -3.5991
ISOC1 isochorismatase domain containing 1 -3.29815
PCDH8 protocadherin 8 -3.2252
MT2A metallothionein 2A -3.1271
MORF4L2 mortality factor 4 like 2 -3.0377
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.9894
CALM2 calmodulin 2 (phosphorylase kinase, delta) -2.97225
ATG4A autophagy related 4A, cysteine peptidase -2.91255
PABPC1 poly(A) binding protein, cytoplasmic 1 -2.7161
FBXO34 F-box protein 34 -2.52255
IGFBP7 insulin-like growth factor binding protein 7 -2.49088
UBXN2B UBX domain protein 2B -2.45885
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6 -2.4448
ARL17B ADP-ribosylation factor-like 17B -2.38135
WNT8B wingless-type MMTV integration site family, member 8B -2.35265
CHGB chromogranin B -2.34885
RPLP2 ribosomal protein, large, P2 -2.3467
ZKSCAN7 zinc finger with KRAB and SCAN domains 7 -2.3301
NANOS2 nanos homolog 2 (Drosophila) -2.32525
TRAT1 T cell receptor associated transmembrane adaptor 1 -2.30075
SIPA1 signal-induced proliferation-associated 1 -2.2969
MAP1S microtubule-associated protein 1S -2.2879
CD244 CD244 molecule, natural killer cell receptor 2B4 -2.272
PDE3B phosphodiesterase 3B, cGMP-inhibited -2.23247
PLAG1 pleiomorphic adenoma gene 1 -2.20985
FLT3LG fms-related tyrosine kinase 3 ligand -2.1952
RCAN3 RCAN family member 3 -2.1855
HOXD9 homeobox D9 -2.1847
BORCS8 BLOC-1 related complex subunit 8 -2.183
LOC100533997 MAGEA10-MAGEA5 readthrough -2.1819
CTNND1 catenin (cadherin-associated protein), delta 1 -2.16302
TMPRSS5 transmembrane protease, serine 5 -2.16235
MAP9 microtubule-associated protein 9 -2.1357
ZMYM6 zinc finger, MYM-type 6 -2.13115
SERF1A small EDRK-rich factor 1A (telomeric) -2.1174
PCP4 Purkinje cell protein 4 -2.11635
NGFR nerve growth factor receptor -2.11605
USP19 ubiquitin specific peptidase 19 -2.0852
STRN4 striatin, calmodulin binding protein 4 -2.0826
ZMYM3 zinc finger, MYM-type 3 -2.07115
SLC66A2 solute carrier family 66 member 2 -2.07085
SV2C synaptic vesicle glycoprotein 2C -2.0685
MEIS1 Meis homeobox 1 -2.06765
PDCD10 programmed cell death 10 -2.0584
ZNF354A zinc finger protein 354A -2.03885
CORO2A coronin, actin binding protein, 2A -2.03365
ZNF223 zinc finger protein 223 -2.02575
MARCKSL1 MARCKS-like 1 -2.0173
EDN2 endothelin 2 -2.00805
TUBA1C tubulin, alpha 1c -2.00763
KRT5 keratin 5, type II -2.0062
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 -2.00565