CRCGN015_MCF10A_48H:F04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description BRD-K63993117 102.48 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN015_MCF10A_48H:F04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
COQ8A coenzyme Q8A 5.16655
KDM5A lysine (K)-specific demethylase 5A 4.65266
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 3.93986
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.78135
EXOSC4 exosome component 4 2.77781
KDM5D lysine (K)-specific demethylase 5D 2.66255
ADAT1 adenosine deaminase, tRNA-specific 1 2.6191
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.54472
ZNF124 zinc finger protein 124 2.44179
USP9Y ubiquitin specific peptidase 9, Y-linked 2.24456
ZNF573 zinc finger protein 573 2.17665
KLHL21 kelch-like family member 21 2.17525
WDR7 WD repeat domain 7 2.17468
PLXDC2 plexin domain containing 2 2.10602
POLI polymerase (DNA directed) iota 2.07241
TXNL4B thioredoxin-like 4B 2.05624

decreased expression

Symbol Name Standardized Value
CCNB1 cyclin B1 -4.95978
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.64638
SMC1A structural maintenance of chromosomes 1A -3.1069
TM9SF3 transmembrane 9 superfamily member 3 -2.99256
HPRT1 hypoxanthine phosphoribosyltransferase 1 -2.61557
UBA1 ubiquitin-like modifier activating enzyme 1 -2.5385
ANXA3 annexin A3 -2.38191
PRSS23 protease, serine, 23 -2.36112
FOXO4 forkhead box O4 -2.29971
KDM5C lysine (K)-specific demethylase 5C -2.21628
PUDP pseudouridine 5'-phosphatase -2.18545
PLS1 plastin 1 -2.11689
MSN moesin -2.11277