CRCGN015_MCF10A_48H:F11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description cyclohexylamine.hcl 33.82 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

9 genes differentially expressed following the CRCGN015_MCF10A_48H:F11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CHMP6 charged multivesicular body protein 6 3.92808
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.51289
MX1 MX dynamin-like GTPase 1 2.38263
APLP2 amyloid beta (A4) precursor-like protein 2 2.25066
PCSK7 proprotein convertase subtilisin/kexin type 7 2.15663
SIRT7 sirtuin 7 2.02156

decreased expression

Symbol Name Standardized Value
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -7.36358
RPA3 replication protein A3, 14kDa -4.56082
ATG4A autophagy related 4A, cysteine peptidase -2.11432