CRCGN015_MCF10A_48H:F12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description cyclohexylamine.hcl 11.27 um perturbation at 48 h in MCF10A (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

41 genes differentially expressed following the CRCGN015_MCF10A_48H:F12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ANO10 anoctamin 10 5.06908
SPAG4 sperm associated antigen 4 4.51798
ZW10 zw10 kinetochore protein 4.01214
HLA-DRA major histocompatibility complex, class II, DR alpha 3.05987
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.58493
ALG9 ALG9, alpha-1,2-mannosyltransferase 2.38758
UFSP2 UFM1-specific peptidase 2 2.37601
CHL1 cell adhesion molecule L1-like 2.20614
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.17677
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa 2.17475
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.16586
NKAPD1 NKAP domain containing 1 2.16105
NAV3 neuron navigator 3 2.14703
ERBIN erbb2 interacting protein 2.13488
DERA deoxyribose-phosphate aldolase (putative) 2.12352
CAPN7 calpain 7 2.12315
TBCE tubulin folding cofactor E 2.10452
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic 2.08856
SNX19 sorting nexin 19 2.01492

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -5.42267
PGAM4 phosphoglycerate mutase family member 4 -5.32706
RPA3 replication protein A3, 14kDa -4.97969
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) -3.01139
VIM vimentin -2.88076
CDPF1 cysteine-rich, DPF motif domain containing 1 -2.47058
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 -2.31832
RHOG ras homolog family member G -2.26662
ZDHHC4 zinc finger, DHHC-type containing 4 -2.24343
CD24 CD24 molecule -2.2085
FBXO2 F-box protein 2 -2.19973
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -2.15218
WBP1L WW domain binding protein 1-like -2.1492
MMP15 matrix metallopeptidase 15 (membrane-inserted) -2.11826
HPS6 Hermansky-Pudlak syndrome 6 -2.11307
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) -2.1089
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) -2.1051
ROGDI rogdi homolog (Drosophila) -2.10256
RIPOR2 RHO family interacting cell polarization regulator 2 -2.06131
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa -2.0483
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit -2.04789
ZMIZ1 zinc finger, MIZ-type containing 1 -2.00653