CRCGN015_MCF10A_48H:F14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzoic acid, sodium 33.82 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN015_MCF10A_48H:F14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.3929
KLHL21 kelch-like family member 21 3.23592
SNX11 sorting nexin 11 3.03569
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.28664
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 2.2133
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 2.12005
UQCRH ubiquinol-cytochrome c reductase hinge protein 2.05534

decreased expression

Symbol Name Standardized Value
SNX7 sorting nexin 7 -3.15897
CD24 CD24 molecule -2.89801
KIF16B kinesin family member 16B -2.79713
PCNA proliferating cell nuclear antigen -2.68978
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -2.57554
CSRP2 cysteine and glycine-rich protein 2 -2.52198
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -2.50317
LOC124907782 dual specificity protein phosphatase 22 -2.21232
MKKS McKusick-Kaufman syndrome -2.20615
S100A8 S100 calcium binding protein A8 -2.17233
PANK2 pantothenate kinase 2 -2.0063