CRCGN015_MCF10A_48H:F15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzoic acid, sodium 11.27 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

43 genes differentially expressed following the CRCGN015_MCF10A_48H:F15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 3.64703
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 3.43031
GRWD1 glutamate-rich WD repeat containing 1 3.3819
STK25 serine/threonine kinase 25 3.20476
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 3.03479
FPGS folylpolyglutamate synthase 2.72334
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.58281
FBXL12 F-box and leucine-rich repeat protein 12 2.35458
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 2.27896
HJURP Holliday junction recognition protein 2.25535
TMEM38B transmembrane protein 38B 2.23893
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 2.211
SAP30L SAP30-like 2.20237
SMIM40 small integral membrane protein 40 2.14553
PCM1 pericentriolar material 1 2.13788
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.09959
SLC2A4RG SLC2A4 regulator 2.0461
SNAP25 synaptosomal-associated protein, 25kDa 2.04383
MEF2C myocyte enhancer factor 2C 2.04315

decreased expression

Symbol Name Standardized Value
NRIP1 nuclear receptor interacting protein 1 -3.82525
S100A8 S100 calcium binding protein A8 -3.75398
ANXA3 annexin A3 -3.48435
ABI1 abl-interactor 1 -3.23009
YME1L1 YME1-like 1 ATPase -2.95231
CD58 CD58 molecule -2.91343
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.45209
RIN2 Ras and Rab interactor 2 -2.30484
GABARAPL2 GABA(A) receptor-associated protein-like 2 -2.3024
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.2901
TERT telomerase reverse transcriptase -2.25514
WDR37 WD repeat domain 37 -2.23684
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 -2.15553
CCNB1 cyclin B1 -2.14407
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -2.11419
ZNF248 zinc finger protein 248 -2.09219
EFHC1 EF-hand domain (C-terminal) containing 1 -2.05817
KRT14 keratin 14, type I -2.0566
TMEM123 transmembrane protein 123 -2.04532
KRT4 keratin 4, type II -2.03238
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -2.00997
DDIT4 DNA-damage-inducible transcript 4 -2.00746
SGK1 serum/glucocorticoid regulated kinase 1 -2.00586
NUPR1 nuclear protein, transcriptional regulator, 1 -2.00486