CRCGN015_MCF10A_48H:F19 Gene Set
Genes
48 genes differentially expressed following the CRCGN015_MCF10A_48H:F19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PRMT3
|
protein arginine methyltransferase 3
|
2.49315
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
2.42375
|
|
PDZD8
|
PDZ domain containing 8
|
2.3931
|
|
WRN
|
Werner syndrome, RecQ helicase-like
|
2.3181
|
|
SPDL1
|
spindle apparatus coiled-coil protein 1
|
2.3043
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
2.2873
|
|
LUC7L2
|
LUC7-like 2 (S. cerevisiae)
|
2.25695
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.2351
|
|
TCERG1
|
transcription elongation regulator 1
|
2.16755
|
|
PARP1
|
poly (ADP-ribose) polymerase 1
|
2.16325
|
|
CHRNA5
|
cholinergic receptor, nicotinic, alpha 5 (neuronal)
|
2.16275
|
|
HJURP
|
Holliday junction recognition protein
|
2.159
|
|
LARP1
|
La ribonucleoprotein domain family, member 1
|
2.13902
|
|
ADNP
|
activity-dependent neuroprotector homeobox
|
2.1005
|
|
PDHA1
|
pyruvate dehydrogenase (lipoamide) alpha 1
|
2.04008
|
|
DLK1
|
delta-like 1 homolog (Drosophila)
|
2.0373
|
|
NUP107
|
nucleoporin 107kDa
|
2.0356
|
|
PIGB
|
phosphatidylinositol glycan anchor biosynthesis, class B
|
2.016
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
2.01385
|
|
CAND1
|
cullin-associated and neddylation-dissociated 1
|
2.0094
|
|
SESN1
|
sestrin 1
|
2.0003
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
YME1L1
|
YME1-like 1 ATPase
|
-4.84047
|
|
MSMO1
|
methylsterol monooxygenase 1
|
-4.33665
|
|
S100A8
|
S100 calcium binding protein A8
|
-4.13765
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-3.5338
|
|
ABI1
|
abl-interactor 1
|
-3.31965
|
|
KRT14
|
keratin 14, type I
|
-2.9974
|
|
WDR37
|
WD repeat domain 37
|
-2.77955
|
|
IFRD2
|
interferon-related developmental regulator 2
|
-2.7521
|
|
DUSP14
|
dual specificity phosphatase 14
|
-2.70715
|
|
CSRP2
|
cysteine and glycine-rich protein 2
|
-2.64107
|
|
PRPF18
|
pre-mRNA processing factor 18
|
-2.5577
|
|
PHF11
|
PHD finger protein 11
|
-2.5013
|
|
OAT
|
ornithine aminotransferase
|
-2.4754
|
|
CTSO
|
cathepsin O
|
-2.4342
|
|
MVP
|
major vault protein
|
-2.42895
|
|
SLC35A1
|
solute carrier family 35 (CMP-sialic acid transporter), member A1
|
-2.4072
|
|
HDHD3
|
haloacid dehalogenase-like hydrolase domain containing 3
|
-2.38255
|
|
GLRX
|
glutaredoxin (thioltransferase)
|
-2.31203
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.3057
|
|
PRR15L
|
proline rich 15-like
|
-2.28085
|
|
ACTR1B
|
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
|
-2.28035
|
|
MT2A
|
metallothionein 2A
|
-2.22685
|
|
CTSD
|
cathepsin D
|
-2.1975
|
|
PSME2
|
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
|
-2.07165
|
|
PKP1
|
plakophilin 1
|
-2.05953
|
|
DHRS1
|
dehydrogenase/reductase (SDR family) member 1
|
-2.00775
|
|
CREG1
|
cellular repressor of E1A-stimulated genes 1
|
-2.00475
|
