CRCGN015_MCF10A_48H:F20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description caffeic-acid 32.81 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN015_MCF10A_48H:F20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
BTK Bruton agammaglobulinemia tyrosine kinase 2.54817
PUS7 pseudouridylate synthase 7 (putative) 2.19248
ODF2 outer dense fiber of sperm tails 2 2.1396
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 2.05994

decreased expression

Symbol Name Standardized Value
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -4.67766
OXA1L oxidase (cytochrome c) assembly 1-like -4.50126
KRT14 keratin 14, type I -4.10511
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -4.05103
VDAC1 voltage-dependent anion channel 1 -4.02779
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.75789
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 -3.03957
VIM vimentin -2.60196
MT2A metallothionein 2A -2.33136
MT1X metallothionein 1X -2.3294
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 -2.29418
DAD1 defender against cell death 1 -2.28002
GGCT gamma-glutamylcyclotransferase -2.2745
ATP5F1E ATP synthase F1 subunit epsilon -2.25106
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 -2.22936
GMPR2 guanosine monophosphate reductase 2 -2.1375
AVL9 AVL9 homolog (S. cerevisiase) -2.12504
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -2.0076