CRCGN015_MCF10A_48H:F22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1h-1,2,3-benzotriazole 100.82 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN015_MCF10A_48H:F22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CIAO3 cytosolic iron-sulfur assembly component 3 3.05479
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.6576
GMPS guanine monphosphate synthase 2.36058
ANTKMT adenine nucleotide translocase lysine methyltransferase 2.32874
ZW10 zw10 kinetochore protein 2.32349
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.26207
CCDC85B coiled-coil domain containing 85B 2.18365
WIF1 WNT inhibitory factor 1 2.14644
NT5DC2 5'-nucleotidase domain containing 2 2.11885
CEMIP cell migration inducing protein, hyaluronan binding 2.0903
VIL1 villin 1 2.0787
PDCD10 programmed cell death 10 2.05764
IRF6 interferon regulatory factor 6 2.03584
DEF8 differentially expressed in FDCP 8 homolog (mouse) 2.00221

decreased expression

Symbol Name Standardized Value
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -5.04428
TM9SF3 transmembrane 9 superfamily member 3 -4.74266
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.30391
ANKRD10 ankyrin repeat domain 10 -3.21593
KIF14 kinesin family member 14 -2.92109
MTERF3 mitochondrial transcription termination factor 3 -2.90457
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.41676
MSMO1 methylsterol monooxygenase 1 -2.36186
PLK2 polo-like kinase 2 -2.33492
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 -2.26052
RBM12B RNA binding motif protein 12B -2.22854
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.2015
ANXA3 annexin A3 -2.13383
YTHDC1 YTH domain containing 1 -2.07069
PER3 period circadian clock 3 -2.05991
NIBAN1 niban apoptosis regulator 1 -2.05363
NBPF3 neuroblastoma breakpoint family, member 3 -2.02493