| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | nifedipine 11.22 um perturbation at 48 h in MCF10A (Carcinogenome) |
| Similar Terms | |
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65 genes differentially expressed following the CRCGN015_MCF10A_48H:G03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PRR7 | proline rich 7 (synaptic) | 4.95435 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | 4.9035 |
| STAP2 | signal transducing adaptor family member 2 | 3.9773 |
| RPIA | ribose 5-phosphate isomerase A | 3.85645 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | 3.20545 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | 2.7997 |
| MSRA | methionine sulfoxide reductase A | 2.7382 |
| TLCD3A | TLC domain containing 3A | 2.5526 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | 2.51425 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | 2.41935 |
| NABP2 | nucleic acid binding protein 2 | 2.39505 |
| ZNF146 | zinc finger protein 146 | 2.3887 |
| ZBTB32 | zinc finger and BTB domain containing 32 | 2.35385 |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | 2.3401 |
| SNCAIP | synuclein, alpha interacting protein | 2.23885 |
| WRAP73 | WD repeat containing, antisense to TP73 | 2.21845 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.1764 |
| E2F5 | E2F transcription factor 5, p130-binding | 2.1531 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.1286 |
| TOMM40 | translocase of outer mitochondrial membrane 40 homolog (yeast) | 2.0925 |
| MYOD1 | myogenic differentiation 1 | 2.0885 |
| ZNF556 | zinc finger protein 556 | 2.08425 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 2.07778 |
| PAK1IP1 | PAK1 interacting protein 1 | 2.0699 |
| RAB5C | RAB5C, member RAS oncogene family | 2.06335 |
| CCDC86 | coiled-coil domain containing 86 | 2.06125 |
| GPR18 | G protein-coupled receptor 18 | 2.0589 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 2.01435 |
| POLR1F | RNA polymerase I subunit F | 2.0129 |
| SDHC | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 2.01272 |
| HDHD5 | haloacid dehalogenase like hydrolase domain containing 5 | 2.0104 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GRN | granulin | -6.28698 |
| S100A8 | S100 calcium binding protein A8 | -3.9869 |
| PDLIM1 | PDZ and LIM domain 1 | -3.18135 |
| ANXA3 | annexin A3 | -3.03755 |
| KRT14 | keratin 14, type I | -3.018 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | -2.89295 |
| YY1AP1 | YY1 associated protein 1 | -2.86445 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -2.7598 |
| ATG3 | autophagy related 3 | -2.74503 |
| GLOD4 | glyoxalase domain containing 4 | -2.65085 |
| CCDC28A | coiled-coil domain containing 28A | -2.5414 |
| PTBP2 | polypyrimidine tract binding protein 2 | -2.46175 |
| KIFBP | kinesin family binding protein | -2.4497 |
| MT2A | metallothionein 2A | -2.4 |
| PCNP | PEST proteolytic signal containing nuclear protein | -2.3953 |
| GMPS | guanine monphosphate synthase | -2.3379 |
| ERCC5 | excision repair cross-complementation group 5 | -2.29015 |
| CTC1 | CTS telomere maintenance complex component 1 | -2.27885 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | -2.2663 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -2.26175 |
| VPS26A | vacuolar protein sorting 26 homolog A (S. pombe) | -2.2356 |
| CFP | complement factor properdin | -2.2263 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -2.22592 |
| CCDC92 | coiled-coil domain containing 92 | -2.215 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -2.20405 |
| STXBP2 | syntaxin binding protein 2 | -2.18995 |
| TFG | TRK-fused gene | -2.1654 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.10095 |
| CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 | -2.06575 |
| MACO1 | macoilin 1 | -2.04535 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | -2.03422 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.0096 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -2.0045 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 | -2.00265 |
