| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2-chloroacetophenone 101.98 um perturbation at 48 h in MCF10A (Carcinogenome) |
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60 genes differentially expressed following the CRCGN015_MCF10A_48H:G07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUCB2 | nucleobindin 2 | 5.72529 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 5.58916 |
| STAP2 | signal transducing adaptor family member 2 | 3.38262 |
| WIF1 | WNT inhibitory factor 1 | 3.03373 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 2.96626 |
| CCDC85B | coiled-coil domain containing 85B | 2.95903 |
| CDKN2AIP | CDKN2A interacting protein | 2.71556 |
| NRBF2 | nuclear receptor binding factor 2 | 2.67549 |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D | 2.58354 |
| HOXA10 | homeobox A10 | 2.49572 |
| HAUS3 | HAUS augmin-like complex, subunit 3 | 2.38866 |
| NKRF | NFKB repressing factor | 2.33782 |
| FUBP3 | far upstream element (FUSE) binding protein 3 | 2.3158 |
| FBXO34 | F-box protein 34 | 2.28243 |
| OBI1 | ORC ubiquitin ligase 1 | 2.22717 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 2.20442 |
| DNAAF2 | dynein, axonemal, assembly factor 2 | 2.19353 |
| ERI2 | ERI1 exoribonuclease family member 2 | 2.18899 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | 2.17922 |
| ZNF184 | zinc finger protein 184 | 2.16436 |
| ZNF267 | zinc finger protein 267 | 2.15931 |
| PARG | poly (ADP-ribose) glycohydrolase | 2.153 |
| GET1 | guided entry of tail-anchored proteins factor 1 | 2.12379 |
| RLF | rearranged L-myc fusion | 2.12223 |
| CD320 | CD320 molecule | 2.09388 |
| UBXN2B | UBX domain protein 2B | 2.09204 |
| TRAPPC11 | trafficking protein particle complex 11 | 2.06267 |
| TBK1 | TANK-binding kinase 1 | 2.02562 |
| ARFIP1 | ADP-ribosylation factor interacting protein 1 | 2.01884 |
| AGA | aspartylglucosaminidase | 2.01411 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -4.95049 |
| ADI1 | acireductone dioxygenase 1 | -4.8042 |
| STXBP2 | syntaxin binding protein 2 | -4.00339 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -3.93544 |
| CDC25B | cell division cycle 25B | -3.08768 |
| HSPB1 | heat shock 27kDa protein 1 | -2.97646 |
| MT2A | metallothionein 2A | -2.91556 |
| GFUS | GDP-L-fucose synthase | -2.76638 |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | -2.74497 |
| COQ9 | coenzyme Q9 | -2.6527 |
| PRKCD | protein kinase C, delta | -2.58574 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | -2.48818 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.42251 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -2.36078 |
| PUF60 | poly-U binding splicing factor 60KDa | -2.29986 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -2.28292 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | -2.23526 |
| ARHGAP4 | Rho GTPase activating protein 4 | -2.22392 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -2.20903 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -2.20683 |
| HMG20B | high mobility group 20B | -2.18415 |
| MVP | major vault protein | -2.1374 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 | -2.13053 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -2.08304 |
| TRABD | TraB domain containing | -2.06855 |
| NUAK2 | NUAK family, SNF1-like kinase, 2 | -2.06285 |
| GPS1 | G protein pathway suppressor 1 | -2.05933 |
| PLK1 | polo-like kinase 1 | -2.05892 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -2.03906 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -2.01637 |