CRCGN015_MCF10A_48H:G08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-chloroacetophenone 33.99 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN015_MCF10A_48H:G08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.39141
SNAP25 synaptosomal-associated protein, 25kDa 3.68701
MCOLN1 mucolipin 1 3.39837
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.35148
RPH3A rabphilin 3A 2.9255
SV2B synaptic vesicle glycoprotein 2B 2.78675
PDIA5 protein disulfide isomerase family A, member 5 2.76287
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 2.51513
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 2.47571
ENOX1 ecto-NOX disulfide-thiol exchanger 1 2.45517
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 2.41397
SBNO1 strawberry notch homolog 1 (Drosophila) 2.38781
NUTF2 nuclear transport factor 2 2.30103
FBXL4 F-box and leucine-rich repeat protein 4 2.26488
STMN2 stathmin 2 2.10629
MTA2 metastasis associated 1 family, member 2 2.06169
GNG12 guanine nucleotide binding protein (G protein), gamma 12 2.03963

decreased expression

Symbol Name Standardized Value
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -6.35429
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -4.68815
MT2A metallothionein 2A -4.03336
IGFBP7 insulin-like growth factor binding protein 7 -2.75492
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.20078