CRCGN015_MCF10A_48H:G11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-nitrosopyrrolidine 35.0 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

73 genes differentially expressed following the CRCGN015_MCF10A_48H:G11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNX11 sorting nexin 11 4.16685
CD320 CD320 molecule 2.90134
KAT7 K(lysine) acetyltransferase 7 2.87703
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.85869
CCP110 centriolar coiled coil protein 110kDa 2.81378
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.6608
ATXN3 ataxin 3 2.50034
PNPO pyridoxamine 5'-phosphate oxidase 2.4971
IGHMBP2 immunoglobulin mu binding protein 2 2.47046
C2CD5 C2 calcium-dependent domain containing 5 2.41006
CBX1 chromobox homolog 1 2.33378
CENPS-CORT CENPS-CORT readthrough 2.33345
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 2.28672
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 2.23903
EBI3 Epstein-Barr virus induced 3 2.22064
ATP5MC1 ATP synthase membrane subunit c locus 1 2.21036
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa 2.18668
THAP1 THAP domain containing, apoptosis associated protein 1 2.14907
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) 2.14772
SLAMF1 signaling lymphocytic activation molecule family member 1 2.11833
SFXN1 sideroflexin 1 2.11153
COQ3 coenzyme Q3 methyltransferase 2.10047
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) 2.05549
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.05488
CENPM centromere protein M 2.04282
PIR pirin (iron-binding nuclear protein) 2.03876
UNKL unkempt family zinc finger-like 2.01393

decreased expression

Symbol Name Standardized Value
VIM vimentin -5.99547
S100A8 S100 calcium binding protein A8 -4.84197
SNX7 sorting nexin 7 -4.76312
GNAS GNAS complex locus -4.43691
ADI1 acireductone dioxygenase 1 -4.28663
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -4.28368
CALM2 calmodulin 2 (phosphorylase kinase, delta) -3.63238
RPS5 ribosomal protein S5 -3.51975
RPL38 ribosomal protein L38 -3.31519
RPL3 ribosomal protein L3 -3.25492
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 -3.17081
TUBA1C tubulin, alpha 1c -2.9991
TUBA1B tubulin, alpha 1b -2.89041
OAT ornithine aminotransferase -2.76815
RPS19 ribosomal protein S19 -2.6961
RPLP2 ribosomal protein, large, P2 -2.68898
TUBA1A tubulin, alpha 1a -2.68695
RPL19 ribosomal protein L19 -2.64041
ATP5F1E ATP synthase F1 subunit epsilon -2.33915
ART3 ADP-ribosyltransferase 3 -2.32581
PABPC1 poly(A) binding protein, cytoplasmic 1 -2.31756
RPL29 ribosomal protein L29 -2.29172
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.275
CIB1 calcium and integrin binding 1 (calmyrin) -2.25449
TMEM147 transmembrane protein 147 -2.239
SOX11 SRY (sex determining region Y)-box 11 -2.22271
HLA-A major histocompatibility complex, class I, A -2.2089
TBCB tubulin folding cofactor B -2.20516
TTLL4 tubulin tyrosine ligase-like family member 4 -2.20191
NELFCD negative elongation factor complex member C/D -2.18623
RPL18 ribosomal protein L18 -2.18513
RPS13 ribosomal protein S13 -2.18258
RPL12 ribosomal protein L12 -2.16392
RBM42 RNA binding motif protein 42 -2.15071
RPL27A ribosomal protein L27a -2.10765
HLA-C major histocompatibility complex, class I, C -2.10035
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -2.0919
RPL10A ribosomal protein L10a -2.08826
F5 coagulation factor V (proaccelerin, labile factor) -2.08089
RPS15 ribosomal protein S15 -2.07571
EIF3L eukaryotic translation initiation factor 3, subunit L -2.07438
KRT14 keratin 14, type I -2.06403
PHF10 PHD finger protein 10 -2.06358
MRPL13 mitochondrial ribosomal protein L13 -2.04112
RPL9 ribosomal protein L9 -2.01465
RPS8 ribosomal protein S8 -2.00867