CRCGN015_MCF10A_48H:G12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-nitrosopyrrolidine 11.67 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN015_MCF10A_48H:G12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PDIA5 protein disulfide isomerase family A, member 5 3.72806
SNX11 sorting nexin 11 3.507
WDR7 WD repeat domain 7 2.89768
RBM7 RNA binding motif protein 7 2.14066
TSEN2 TSEN2 tRNA splicing endonuclease subunit 2.02459

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -8.24327
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.7079
PLS1 plastin 1 -4.20278
KRT14 keratin 14, type I -4.0553
CSRP2 cysteine and glycine-rich protein 2 -3.24159
PCCB propionyl CoA carboxylase, beta polypeptide -3.20523
DYNLT3 dynein, light chain, Tctex-type 3 -2.88837
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.60731
CANT1 calcium activated nucleotidase 1 -2.158
VIM vimentin -2.1452
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) -2.07519